Latest Advances

  • Condition: Children With Congenital Adrenal Hyperplasia due to Steroid 21-Hydroxylase Deficiency
  • Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences
  • Treatment Used: Letrozole
  • Number of Patients: 28
  • Published —
The purpose of the study was to assess the effectiveness of letrozole in treatment of children with congenital adrenal hyperplasia due to steroid 21-hydroxylase deficiency.
  • Condition: McCune-Albright Syndrome Girls
  • Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences
  • Treatment Used: Letrozole
  • Number of Patients: 21
  • Published —
The study researched the use of letrozole for girls with McCune-Albright syndrome.
  • Condition: Precocious Puberty (PP)
  • Journal: Journal of pediatric endocrinology & metabolism : JPEM
  • Treatment Used: Vitamin D
  • Number of Patients: 0
  • Published —
This review of the literature focused on the association between vitamin D deficiency and precocious puberty (PP).
  • Condition: Children with Precocious Puberty (CPP)
  • Journal: Clinics (Sao Paulo, Brazil)
  • Treatment Used: Gonadotropin-Releasing Hormone Analog Treatment
  • Number of Patients: 24
  • Published —
This study evaluated the cut-off values of stimulated leuteinizing hormone that determine gonadotrophic suppression in patients diagnosed with central precocious puberty (CPP).
  • Condition: Central Precocious Puberty (CPP) or Early and Fast Puberty (EEP) in Chinese Girls
  • Journal: The Journal of clinical endocrinology and metabolism
  • Treatment Used: Gonadotropin-Releasing Hormone Analogues (GnRHa) and Recombinant Human Growth Hormone (rhGH)
  • Number of Patients: 448
  • Published —
This study assessed the effects of long-term treatment for central precocious puberty (CPP) or early and fast puberty (EFP) on final adult height (FAH) and its main influencing factors.
  • Condition: Overweight/Obese and Normal-Weight Children with Idiopathic Central Precocious Puberty (CPP)
  • Journal: Journal of pediatric endocrinology & metabolism : JPEM
  • Treatment Used: Gonadotropin-Releasing Hormone Analogs (GnRHa)
  • Number of Patients: 58
  • Published —
This study investigated the effect of gonadotropin-releasing hormone analogues (GnRHa) on body mass index (BMI) standard deviation score (SDS), and the influence of body mass index status on treatment outcomes in children with idiopathic (of unknown cause) central precocious puberty (iCPP).
  • Condition: Children with Central Precocious Puberty (CPP), Early Puberty, or Short Stature
  • Journal: Journal of pediatric endocrinology & metabolism : JPEM
  • Treatment Used: Gonadotropin-Releasing Hormone Agonist Therapy (GnRHa)
  • Number of Patients: 0
  • Published —
This study examined the effects of gonadotropin-releasing hormone agonists (GnRHa) therapy in both genders and in subjects treated for central precocious puberty (CPP), early puberty, or short stature.
  • Condition: Girls with Central Precocious Puberty
  • Journal: Journal of pediatric endocrinology & metabolism : JPEM
  • Treatment Used: Gonadotropin-Releasing Hormone Agonist (GnRHa)
  • Number of Patients: 66
  • Published —
This study evaluated the emotional and behavioral status of patients with precocious puberty and analyzed the effect of gonadotropin-releasing hormone agonist (GnRHa) treatment.
  • Condition: Fibrous dysplasia/McCune-Albright syndrome (FD/MAS) Refractory To Bisphosphonate Therapy
  • Journal: The Journal of clinical endocrinology and metabolism
  • Treatment Used: Denosumab
  • Number of Patients: 12
  • Published —
This study evaluated the effectiveness of the receptor activator of nuclear factor-?B ligand inhibitor denosumab (antiresorptive agent) in the treatment of patients with fibrous dysplasia/McCune-Albright syndrome (FD/MAS) refractory to bisphosphonate therapy (help prevent or slow down bone thinning or osteoporosis).
  • Condition: Severely Advanced Bone Age in Congenital Adrenal Hyperplasia
  • Journal: Hormone research in paediatrics
  • Treatment Used: Aromatase Inhibitor
  • Number of Patients: 1
  • Published —
The study researched the effects of aromatase inhibitors (stops the turning of androgen turning into estrogen) for severely advanced bone age in congenital adrenal hyperplasia.
  • Condition: Girls with Idiopathic Precocious Puberty (iCPP)
  • Journal: Journal of clinical research in pediatric endocrinology
  • Treatment Used: Depot Leuprolide Acetate (LA)
  • Number of Patients: 220
  • Published —
This study evaluated the effectiveness of monthly 3.75 mg dose of leuprolide acetate (LA) to suppress the hypothalamo-pituitary-gonadal (HPG) axis in girls with idiopathic central precocious puberty (iCPP).
  • Condition: Polyostotic Craniomaxillofacial Fibrous Dysplasia Associated with Acromegalia/McCune-Albright Syndrome (MAS)
  • Journal: The Journal of craniofacial surgery
  • Treatment Used: Surgical Re-Alignment
  • Number of Patients: 1
  • Published —
This article described the case of a patient with polyostotic craniomaxillofacial fibrous dysplasia (disorder that features the replacement of multiple areas of bone by fibrous tissue) associated with acromegalia (excess amount of growth hormone), along with McCune-Albright syndrome (genetic disorder affecting the bone, skin and endocrine systems; MAS) treated with surgical re-alignment.
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