The ACHIEVE Trial: Achieving Longer Gestation in Preeclampsia Via Antihypertensive Therapy.
The Achieve Trial is a randomized clinical trial to test whether lowering blood pressure to less than 140/90 mmHg in women with hypertensive disorders of pregnancy will prolong pregnancy.
• Pregnant women
• Gestational age: 23 weeks, 0 days to 35 weeks, 6 days
• Hypertensive disorder of pregnancy including gestational hypertension or preeclampsia, the non-severe form at enrollment, which is called without severe features by the American College of Obstetricians and Gynecologists.
• No evidence of the severe form of preeclampsia, termed severe features, as outlined in maternal exclusions
• No indication for delivery at the time of enrollment.
• Planned expectant management at time of enrollment
• Singleton or dichorionic twin gestation, defined at and beyond 14 weeks gestation. (A pregnancy complicated by a vanishing twin in the first trimester defined as less than 14 weeks gestation will be eligible.)
• Intact membranes