Aspirin for the Treatment of Vascular Dysfunction After Preeclampsia
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Early Phase 1
SUMMARY
Women who develop preeclampsia during pregnancy are four times more likely to develop cardiovascular disease later in life, even if they are otherwise healthy. The reason why this occurs may be related to lasting blood vessel damage after the pregnancy but there are currently no specific treatment strategies to prevent this disease progression. This study addresses this public health issue by examining whether starting low dose aspirin therapy after pregnancy is an effective treatment for lasting blood vessel damage in order to inform better clinical management of cardiovascular disease risk in women who have had preeclampsia.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 50
Healthy Volunteers: f
View:
• had preeclampsia in the past 5 years,
• 18 years or older
Locations
United States
Iowa
University of Iowa
RECRUITING
Iowa City
Contact Information
Primary
Anna Reid-Stanhewicz, PHD
anna-stanhewicz@uiowa.edu
319-467-1732
Time Frame
Start Date: 2023-11-01
Estimated Completion Date: 2026-02
Participants
Target number of participants: 40
Treatments
Placebo_comparator: placebo
placebo pill taken once daily at bedtime for 12 weeks
Experimental: aspirin
162mg aspirin taken once daily at bedtime for 12 weeks
Related Therapeutic Areas
Sponsors
Leads: Anna Stanhewicz, PhD