Association of Urinary Tract Infection With Preeclampsia During Pregnancy

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

Urinary tract infections (UTIs) are a major clinical issue, especially in pregnant women, due to physiological changes that increase susceptibility. If untreated, UTIs can lead to severe complications like preterm labor and low birth weight. Preeclampsia, a hypertensive disorder affecting 0.2-9.2% of pregnancies, is another leading cause of maternal and fetal complications. The relationship between UTIs and preeclampsia remains controversial, with some studies suggesting an association while others show conflicting results. Research gaps highlight the need for region-specific studies, particularly in Pakistan, where both conditions contribute significantly to maternal and neonatal morbidity. This study aims to investigate the association between UTIs and preeclampsia in pregnant women in Pakistan. It will use a cohort design, enrolling 160 patients (80 with UTIs, 80 without) from the Obstetrics Department of PAF Hospital, Islamabad. Participants will be followed until delivery, with preeclampsia diagnosed based on blood pressure and proteinuria criteria. Data will be analyzed using SPSS to calculate relative risk (RR), with statistical significance set at RR \>1 and p ≤ 0.05. The findings could help improve prenatal care and reduce adverse outcomes in high-risk populations.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 35
Healthy Volunteers: t
View:

• Patients attending OPD for routine antenatal checkup

• Patients diagnosed with UTI as per operational definitions

• Gestational age greater than 20 weeks as per LMP

• Age between 18 to 35 years

Locations
Other Locations
Pakistan
PAF Hospital, Islamabad
RECRUITING
Islamabad
Contact Information
Primary
Wajiha Fatima Resident, MBBS, FCPS (I)
mwajeeha52@gmail.com
+923338747575
Time Frame
Start Date: 2025-01-01
Estimated Completion Date: 2025-04-30
Participants
Target number of participants: 160
Treatments
UTI exposed
Patients suffering from UTI as per protocol
UTI non exposed
Patients having no clinical and laboratory evidence of UTI
Sponsors
Leads: Pakistan Air Force (PAF) Hospital Islamabad

This content was sourced from clinicaltrials.gov