Emotion Regulation Based Internet-delivered Cognitive Behavioural Therapy for Premenstrual Dysphoric Disorder: A Randomised Controlled Trial

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Premenstrual dysphoric disorder (PMDD) is a debilitating cyclic mental disorder affecting about 2-5% of women of reproductive age. PMDD is characterised by recurring emotional, behavioural, cognitive, and somatic symptoms that arise during the luteal (premenstrual) phase of the menstrual cycle and remit shortly after the onset of menses. Although pharmacological interventions are available, many women experience residual symptoms, discontinue treatment or refrain from them because of side effects. Therefore, non-pharmacological treatment options are needed. Preliminary evidence suggests that internet-delivered cognitive behavioural therapy (ICBT) is a promising candidate, but further research is warranted. Also, there is room for treatment improvement. Specifically, it has been suggested that components targeting emotional and interpersonal dysregulation should be incorporated into CBT for PMDD. The current study aims to assess the effects of an ICBT intervention for PMDD incorporating skills training in emotion regulation and interpersonal effectiveness in a randomised controlled trial (RCT).

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 45
Healthy Volunteers: f
View:

• PMDD diagnosis according to DSM-5

• Menstrual cycle length between 23-34 days, i.e., 5-8 cycles in the last six months

• Sufficient proficiency in Swedish to comprehend the treatment materials

• Access to computer/tablet/mobile phone with internet connection

Locations
Other Locations
Sweden
Uppsala university
RECRUITING
Uppsala
Contact Information
Primary
Johanna Motilla Hoppe, PhD
johanna.motilla_hoppe@uu.se
+46735252205
Backup
Monica Buhrman, Associate Professor
Monica.Buhrman@psyk.uu.se
+46 18 471 2126
Time Frame
Start Date: 2025-07-14
Estimated Completion Date: 2028-07
Participants
Target number of participants: 164
Treatments
Experimental: Treatment group
Therapist-guided self-help internet-delivered cognitive behavioural therapy for PMDD
No_intervention: Control group
Waiting list
Sponsors
Collaborators: Linkoeping University, Utah State University, Friedrich-Alexander-Universität Erlangen-Nürnberg
Leads: Uppsala University

This content was sourced from clinicaltrials.gov