Learn About Primary Hyperoxaluria Type 2

What is the definition of Primary Hyperoxaluria Type 2?
Primary hyperoxaluria type 2 is a rare condition characterized by the overproduction of a substance called oxalate (also called oxalic acid). In the kidneys, the excess oxalate combines with calcium to form calcium oxalate, a hard compound that is the main component of kidney stones. Deposits of calcium oxalate can lead to kidney damage, kidney failure, and injury to other organs. Primary hyperoxaluria type 2 is caused by the shortage (deficiency) of an enzyme called glyoxylate reductase/hydroxypyruvate reductase (GRHPR) that normally prevents the buildup of oxalate. This enzyme shortage is caused by genetic changes in the GRHPR gene. Primary hyperoxaluria type 2 is inherited in an autosomal recessive pattern.
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What are the alternative names for Primary Hyperoxaluria Type 2?
  • Primary hyperoxaluria type 2
  • D-glycerate dehydrogenase deficiency
  • Glyceric aciduria
  • Glyoxylate reductase/hydroxypyruvate reductase deficiency
  • HP2
  • Oxalosis 2
Who are the top Primary Hyperoxaluria Type 2 Local Doctors?
JL
Dr. John C. Lieske
Nephrology
Elite
Highly rated in
22
conditions
Nephrology

Mayo Clinic

Rochester, Minnesota

200 1st St Sw 
Rochester, MN 55905

John Lieske is a Nephrologist in Rochester, Minnesota. Dr. Lieske has been practicing medicine for over 36 years and is rated as an Elite doctor by MediFind in the treatment of Primary Hyperoxaluria Type 2. He is also highly rated in 22 other conditions, according to our data. His top areas of expertise are Kidney Stones, Primary Hyperoxaluria, Dent Disease, and Nephrocalcinosis. He is licensed to treat patients in Minnesota. Dr. Lieske is currently accepting new patients.

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TD
Dr. Tsering Dhondup
Nephrology
Elite
Highly rated in
3
conditions
Nephrology

Providence Health & Services

Memorial Nephrology Associates PLLC

3525 Ensign Rd Ne 
Olympia, WA 98506

Tsering Dhondup is a Nephrologist in Olympia, Washington. Dr. Dhondup has been practicing medicine for over 22 years and is rated as an Elite doctor by MediFind in the treatment of Primary Hyperoxaluria Type 2. He is also highly rated in 3 other conditions, according to our data. His top areas of expertise are Primary Hyperoxaluria Type 2, Chronic Kidney Disease, Primary Hyperoxaluria, and Kidney Stones. He is licensed to treat patients in Washington. Dr. Dhondup is currently accepting new patients.

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DM
Dr. Dawn S. Milliner
Nephrology
Elite
Highly rated in
9
conditions
Nephrology

Rochester, Minnesota

200 1st St Sw 
Rochester, MN 55905

Dawn Milliner is a Nephrologist in Rochester, Minnesota. Dr. Milliner has been practicing medicine for over 46 years and is rated as an Elite doctor by MediFind in the treatment of Primary Hyperoxaluria Type 2. She is also highly rated in 9 other conditions, according to our data. Her top areas of expertise are Primary Hyperoxaluria, Kidney Stones, Nephrocalcinosis, and Primary Hyperoxaluria Type 1. She is licensed to treat patients in Minnesota.

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What are the latest Primary Hyperoxaluria Type 2 Clinical Trials?
Rare Kidney Stone Consortium Biobank, Rare Diseases Clinical Research Network
Status: Recruiting
Start Date: May 2013
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Summary: This study is being done to obtain samples from patients with primary hyperoxaluria, cystinuria, adenine phosphoribosyl transferase (APRT) deficiency, and Dent disease, and from their family members, for use in future research.
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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center

What are the Latest Advances for Primary Hyperoxaluria Type 2?

There is no recent research available for this condition. Please check back because thousands of new papers are published every week and we strive to find and display the most recent relevant research as soon as it is available.