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Learn About Progressive Multifocal Leukoencephalopathy

What is the definition of Progressive Multifocal Leukoencephalopathy?
Progressive multifocal leukoencephalopathy (PML) is a neurological disorder that damages the myelin that covers and protects nerves in the white matter of the brain. It is caused by the JC virus (JCV). The disease occurs, rarely, in organ transplant patients; people undergoing chronic corticosteroid or immunosuppressive therapy; and individuals with cancer, such as Hodgkin’s disease, lymphoma, and sarcoidosis. PML is most common among individuals with acquired immune deficiency syndrome (AIDS).
What are the alternative names for Progressive Multifocal Leukoencephalopathy?
  • Progressive multifocal leukoencephalopathy
  • Leukoencephalopathy, progressive multifocal
  • PML
Who are the top Progressive Multifocal Leukoencephalopathy Local Doctors?
Igor J. Koralnik
Elite in Progressive Multifocal Leukoencephalopathy
Elite in Progressive Multifocal Leukoencephalopathy

Regenstein Center For Neurological Care - Lavin Family Pavilion

259 E Erie St, Ste 1900, 
Chicago, IL 
Languages Spoken:
English
Accepting New Patients
Offers Telehealth

Igor Koralnik is a Neurologist in Chicago, Illinois. Dr. Koralnik is rated as an Elite provider by MediFind in the treatment of Progressive Multifocal Leukoencephalopathy. His top areas of expertise are Progressive Multifocal Leukoencephalopathy, CACH Syndrome, Encephalitis, Thrombectomy, and Endovascular Embolization. Dr. Koralnik is currently accepting new patients.

Elite in Progressive Multifocal Leukoencephalopathy
Neuroradiology
Elite in Progressive Multifocal Leukoencephalopathy
Neuroradiology

Johns Hopkins Hospital

600 N Wolfe St, 
Baltimore, MD 
Languages Spoken:
English

Daniel Reich is a Neuroradiologist in Baltimore, Maryland. Dr. Reich is rated as an Elite provider by MediFind in the treatment of Progressive Multifocal Leukoencephalopathy. His top areas of expertise are Multiple Sclerosis (MS), CACH Syndrome, Progressive Multifocal Leukoencephalopathy, and Encephalitis.

 
 
 
 
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Elite in Progressive Multifocal Leukoencephalopathy
Elite in Progressive Multifocal Leukoencephalopathy

Office

Nih Clinical Ctr, 
Bethesda, MD 
Languages Spoken:
English

Nancy Richert is a Radiologist in Bethesda, Maryland. Dr. Richert is rated as an Elite provider by MediFind in the treatment of Progressive Multifocal Leukoencephalopathy. Her top areas of expertise are Progressive Multifocal Leukoencephalopathy and Relapsing Multiple Sclerosis (RMS).

What are the latest Progressive Multifocal Leukoencephalopathy Clinical Trials?
CurePML - Allogeneic HPyV-2-specific T-cell Therapy in Patients With Progressive Multifocal Leukoencephalopathy

Summary: There is no approved standard treatment für progressive multifocal leukoencephalopathy (PML). The sponsor of the study is developing a new treatment. For this reason, the investigational medicinal product (IMP) called 'human allogenic HPyV-2-specific T cells' is to be tested in this study. The sponsor wants to find out whether the IMP is safe, influences the neurological status and improves the qu...

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Natural History Study of Progressive Multifocal Leukoencephalopathy (PML)

Background: \- Progressive multifocal leukoencephalopathy (PML) is a severe viral infection of the brain. It is caused by JC virus. Many people have this virus in their bodies all their life, but it is usually kept in check by their immune system. If the immune system does not work right because of a disease or medication, the virus becomes active and can damage cells in the brain. Not much is known about PML...

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Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center