Prurigo Nodularis Overview

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Learn About Prurigo Nodularis

What is the definition of Prurigo Nodularis?
Prurigo nodularis (PN) is a skin disease that causes hard, itchy lumps (nodules) to form on the skin. The itching (pruritus) can be intense, causing people to scratch themselves to the point of bleeding or pain. Scratching can cause more skin lesions to appear. In some cases, people with PN have a history of other diseases including eczema (atopic dermatitis), lymphoma, HIV infection, severe anemia, or kidney disease. The exact cause of PN is unknown. Although scratching is known to cause more nodules to appear, it is unclear what causes the itching to develop in the first place. Diagnosis of the disease is based on observing signs such as extremely itchy skin with the formation of nodules. In some cases, a skin biopsy is used to confirm the diagnosis.
What are the alternative names for Prurigo Nodularis?
  • Prurigo nodularis
  • Nodular prurigo
Who are the top Prurigo Nodularis Local Doctors?
Elite in Prurigo Nodularis
Dr. Nicholas K. Mollanazar
Dermatology
Elite in Prurigo Nodularis
Dr. Nicholas K. Mollanazar
Dermatology

Penn Dermatology Perelman

3400 Civic Center Boulevard, South Pavilion, 1st Floor, 
Philadelphia, PA 
215-662-2737
Languages Spoken:
English
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Accepting New Patients

Nicholas Mollanazar is a Dermatologist in Philadelphia, Pennsylvania. Dr. Mollanazar is rated as an Elite provider by MediFind in the treatment of Prurigo Nodularis. His top areas of expertise are Prurigo Nodularis, Hidradenitis Suppurativa, Liver Spots, and Universal Acquired Melanosis. Dr. Mollanazar is currently accepting new patients.

Elite in Prurigo Nodularis
Dr. Shawn G. Kwatra
Dermatology
Elite in Prurigo Nodularis
Dr. Shawn G. Kwatra
Dermatology
250 W Pratt St, Suite 900, 
Baltimore, MD 
Languages Spoken:
English, Hindi
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Accepting New Patients

Shawn Kwatra is a Dermatologist in Baltimore, Maryland. Dr. Kwatra is rated as an Elite provider by MediFind in the treatment of Prurigo Nodularis. His top areas of expertise are Prurigo Nodularis, Atopic Dermatitis, Lichen Simplex Chronicus, and Actinic Keratosis. Dr. Kwatra is currently accepting new patients.

 
 
 
 
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Elite in Prurigo Nodularis
Sonja Stander
Elite in Prurigo Nodularis
Sonja Stander
Von Esmarch Str. 58, 
Muenster, NW, DE 

Sonja Stander practices in Muenster, Germany. Ms. Stander is rated as an Elite expert by MediFind in the treatment of Prurigo Nodularis. Her top areas of expertise are Prurigo Nodularis, Atopic Dermatitis, Notalgia Paresthetica, and Lichen Simplex Chronicus.

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What are the latest Prurigo Nodularis Clinical Trials?
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis
Enrollment Status: Recruiting
Publish Date: October 14, 2025
Intervention Type: Drug
Study Phase: Phase 3

Summary: The purpose of this study is to evaluate effect of povorcitinib on itch and skin lesions in participants with prurigo nodularis.

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A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis
Enrollment Status: Recruiting
Publish Date: October 14, 2025
Intervention Type: Drug
Study Phase: Phase 3

Summary: The purpose of this study is to evaluate effect of povorcitinib on itch and skin lesions in participants with prurigo nodularis.

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Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center