Structural and Functional Networks in ALS: An Insight Into Pseudobulbar Affect
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The investigators aim to elucidate characteristics of structural and functional brain connectivity in patients with amyotrophic lateral sclerosis (ALS) and pseudobulbar affect (PBA) using diffusion kurtosis imaging (DKI) and magnetoencephalography (MEG).
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 90
Healthy Volunteers: t
View:
• Diagnosed with ALS in the last 6 months according to Gold Coast Criteria
Locations
Other Locations
Denmark
Aalborg University hospital
RECRUITING
Aalborg
Contact Information
Primary
Christian Holm Steenkjær
c.steenkjaer@rn.dk
+4597660000
Backup
Blicher
Au568472@uni.au.dk
+4522144295
Time Frame
Start Date: 2024-05-26
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 50
Treatments
Active_comparator: Control
Sex- and age matched, healthy control. Will only have baseline DKI and MEG performed.
Active_comparator: ALS without PBA
ALS patient without PBA, either at baseline and 6 month follow-up
Active_comparator: ALS with PBA
ALS patient with PBA, either at baseline or follow-up
Related Therapeutic Areas
Sponsors
Collaborators: University of Aarhus
Leads: Aalborg University Hospital