Phenotypical Und Functional Characterization of Macrophages in Critically Ill Patients With Pseudomonas Aeruginosa Induced Sepsis
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
The present study focuses on patients with Pseudomonas aeruginosa (PSA) sepsis. The aim of the present study is to find out whether the M1 (pro-inflammatory) or M2 (anti-inflammatory) phenotype predominates in blood monocytes in critically ill patients with PSA-sepsis, and whether the severity of sepsis and outcome is associated with distinct monocyte phenotype and function.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 90
Healthy Volunteers: t
View:
• age \> 18 years
• critically ill patients with sepsis
• microbiologically proven infection with Pseudomonas aeruginosa
Locations
Other Locations
Germany
Clinic of Anesthesiology
RECRUITING
Ulm
Contact Information
Primary
Manfred Weiss, MD, MBA
manfred.weiss@uniklinik-ulm.de
+49 731 500 60226
Backup
Eberhard Barth, MD
eberhard.barth@uniklinik-ulm.de
+49 731 500 60050
Time Frame
Start Date: 2014-08
Estimated Completion Date: 2026-12
Participants
Target number of participants: 100
Related Therapeutic Areas
Sponsors
Leads: University of Ulm