A Multicenter, Randomized, Double-blind Phase 2 Clinical Study Evaluating the Efficacy and Safety of Different Administration Regimens of HB0017 Injection in Patients With Moderate to Severe Plaque Psoriasis
Status: Recruiting
Location: See all (18) locations...
Intervention Type: Biological
Study Type: Interventional
Study Phase: Phase 2
SUMMARY
This study is a randomized, double-blind phase 2 clinical trial aimed at exploring the efficacy, safety, and immunogenicity of HB0017 injection with different dosing regimens in the treatment of moderate to severe plaque psoriasis in subjects
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:
• Male or female subjects aged 18-75 years (inclusive)
• Chronic plaque psoriasis (PSO) for at least 6 months prior to the randomization.
• Psoriasis Area Severity Index (PASI) \>=12 and body surface area (BSA) affected by PSO \>=10% and Static Physician Global Assessment (sPGA) score \>=3.
• Subjects who are suitable for systemic treatment or phototherapy for psoriasis as judged by the investigator
• Subjects who are able to use effective contraception from the screening period to 6 months after the last dose
Locations
Other Locations
China
The First Affiliated Hospital of Bengbu Medical College
RECRUITING
Bengbu
Jilin University Second Hospital
RECRUITING
Changchun
Xiangya Hospital of Central South University
RECRUITING
Changsha
Sichuan Provincial People's Hospital
RECRUITING
Chengdu
Chongqing Traditional Chinese Medicine Hospital
RECRUITING
Chongqing
Guangdong Provincial People's Hospital
RECRUITING
Guangzhou
Southern Medical University Dermatology Hospital
RECRUITING
Guangzhou
Hangzhou First People's Hospital
RECRUITING
Hangzhou
The First Affiliated Hospital of Zhejiang University School of Medicine
RECRUITING
Hangzhou
Jiaxing First Hospital
RECRUITING
Jiaxing
Shandong First Medical University Affiliated Dermatology Hospital
NOT_YET_RECRUITING
Jinan
Jining First People's Hospital
RECRUITING
Jining
Ningbo Second Hospital
RECRUITING
Ningbo
Shanxi Medical University Second Hospital
RECRUITING
Taiyuan
Wenzhou Medical University Affiliated First Hospital