The Associations Between EIT and Clinical Measures During Standard of Care Procedures in Patients With Respiratory Disease: A Preliminary Study
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
The purpose of this study is to evaluate the Genesis Electrical Impedance Tomography (EIT) imaging system for use in pediatric respiratory disease populations including neuromuscular and bronchopulmonary dysplasia, as well as in age and height matched controls. The EIT does not use radiation, and is read through electrodes.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 14 days
Maximum Age: 40
Healthy Volunteers: t
View:
• 2 weeks old - 40 years old
• Premature infants with current age \>2 weeks with a confirmed diagnosis of BPD based on NIH criteria
• Or Chronic respiratory disease due to underlying neuromuscular disease
• Or confirmed neuromuscular disease with an echo completed within the preceding 12 months of study participation of DMD or other diagnoses associated with mild cardiomyopathy.
• have had a VQ scan
• will be undergoing cardiac catherization for for pulmonary vein stenosis, pulmonary hypertension and/or pulmonary artery stenosis
• Or healthy controls
Locations
United States
Colorado
Children's Hospital Colorado
RECRUITING
Aurora
Contact Information
Primary
Emily DeBoer, MD
emily.deboer@childrenscolorado.org
720-777-4953
Time Frame
Start Date:2019-05-03
Estimated Completion Date:2024-11-30
Participants
Target number of participants:90
Treatments
Premature Infants
Premature infants \>1 month of age currently hospitalized with bronchopulmonary dysplasia (BPD) without acute respiratory infection
Chronic Respiratory Disease
Participants ages \>1 month-21 years with chronic respiratory disease due to underlying neuromuscular disease
Neuromuscular Disease
Participants ages 21-40 years with confirmed neuromuscular disease with an echo completed within the preceding 12 months of study participation of Duchenne muscular dystrophy (DMD) or other diagnoses associated with mild cardiomyopathy
Healthy Controls
Age and height matched healthy controls
V/Q Scan validation
Adults or children who are having or have recently had a V/Q scan
Premature Infants (Longitudinal Cohort)
Premature infants ages 2 weeks to 1 year with diagnosed or suspected bronchopulmonary dysplasia
Pulmonary Vein/Artery Stenosis
Children age 2 months to 18 years, who will be undergoing cardiac catheterization for pulmonary vein stenosis, pulmonary hypertension and/or pulmonary artery stenosis