Learn About Pyoderma Gangrenosum

What is the definition of Pyoderma Gangrenosum?
Pyoderma gangrenosum is a rare, destructive inflammatory skin disease of which a painful nodule or pustule breaks down to form a progressively enlarging ulcer. Lesions may occur either in the absence of any apparent underlying disorder or in association with other diseases, such as ulcerative colitis, Crohn's disease, polyarthritis (an inflammation of several joints together), gammopathy, vasculitis, leukemia, and other conditions. Each year in the United States, Pyoderma gangrenosum occurs in about 1 person per 100,000 people. Pyoderma gangrenosum belongs to a group of autoinflammatory skin diseases called neutrophilic dermatoses. Neutrophils are a type of white blood cell or leukocyte which form an early line of defense against bacterial infections. Ulcerations associated with Pyoderma gangrenosum may occur after trauma or injury to the skin, a process called pathergy.
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What are the alternative names for Pyoderma Gangrenosum?
  • Pyoderma gangrenosum
Who are the top Pyoderma Gangrenosum Local Doctors?
AO
Dr. Alex G. Ortega-Loayza
Dermatology
Elite
Highly rated in
26
conditions
Dermatology

OHSU

OHSU Wound Care Center, Marquam Hill

3270 Sw Pavilion Loop, 
Portland, OR 

Alex Ortega-Loayza is a Dermatologist in Portland, Oregon. Ortega-Loayza has been practicing medicine for over 18 years and is rated as an Elite expert by MediFind in the treatment of Pyoderma Gangrenosum. He is also highly rated in 26 other conditions, according to our data. His top areas of expertise are Pyoderma Gangrenosum, Psoriasis, Calciphylaxis, and Acute Febrile Neutrophilic Dermatosis. He is licensed to treat patients in Oregon and Virginia. Ortega-Loayza is currently accepting new patients.

AM
Angelo V. Marzano
Elite
Highly rated in
59
conditions

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

Pediatric Dermatology Unit, 
Milan, IT 

Angelo Marzano practices in Milan, Italy. Marzano is rated as an Elite expert by MediFind in the treatment of Pyoderma Gangrenosum. He is also highly rated in 59 other conditions, according to our data. His top areas of expertise are Acute Febrile Neutrophilic Dermatosis, Pyoderma Gangrenosum, Pustules, and Steatocystoma Multiplex.

 
 
 
 
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RK
Dr. Robert S. Kirsner
Dermatology
Elite
Highly rated in
18
conditions
Dermatology

University of Miami Health System

University Of Miami

1400 Nw 12th Ave, 
Miami, FL 

Robert Kirsner is a Dermatologist in Miami, Florida. Kirsner has been practicing medicine for over 34 years and is rated as an Elite expert by MediFind in the treatment of Pyoderma Gangrenosum. He is also highly rated in 18 other conditions, according to our data. His top areas of expertise are Pyoderma Gangrenosum, Livedo Reticularis, Cutaneous T-Cell Lymphoma CTCL, and Granuloma Annulare. He is licensed to treat patients in Florida. Kirsner is currently accepting new patients.

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What are the latest Pyoderma Gangrenosum Clinical Trials?
Post-marketing Observational Study for Humira in Participants Diagnosed With Pyoderma Gangrenosum (PG)
Enrollment Status: Recruiting
Publish Date: August 29, 2022
Study Drugs: Adalimumab
Summary: Pyoderma Gangrenosum (PG) is a rapidly progressive disease and presents as painful, single or multiple lesions, with several clinical variants, in different locations, with a nonspecific histology, which makes the diagnosis challenging and often delayed. The main objective of this study is to estimate the incidence proportion of all the infection reported as adverse drug reaction (ADR) of Humira w...
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Hyperbaric Oxygen Therapy for Pyoderma Gangrenosum As a New Treatment Strategy
Enrollment Status: Not yet recruiting
Publish Date: July 18, 2022
Intervention Type: Drug, Other
Study Phase: Phase 3
Summary: Rationale: Pyoderma gangrenosum (PG) is a rare auto-inflammatory neutrophilic dermatosis characterized by a spectrum of clinical presentations with variable courses. Diagnosis and management are challenging in PG. Treatment, including systemic prednisone and anti-TNF therapy, is directed towards reducing pain and associated inflammation that leads to ulceration. Positive effects of hyperbaric oxyg...
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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center

What are the Latest Advances for Pyoderma Gangrenosum?
Clinical efficacy of human split-thickness skin allograft in patients with pyoderma gangrenosum: a case series.
Condition: Pyoderma Gangrenosum (PG)
Journal: Wounds : a compendium of clinical research and practice
Treatment Used: Human Split-Thickness Skin Graft
Number of Patients: 5
Published: July 26, 2022
Summary: Clinical efficacy of human split-thickness skin allograft in patients with pyoderma gangrenosum: a case series.
Current situation and the latest progress in the treatment of pyoderma gangrenosum.
Condition: Pyoderma Gangrenosum (PG)
Journal: Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns
Treatment Used: Glucocorticoids, Immunosuppressants, Intravenous Immuno- Globulin, and Biologics
Number of Patients: 0
Published: June 28, 2022
Summary: Current situation and the latest progress in the treatment of pyoderma gangrenosum.
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VEXAS syndrome : when do we have to consider it ?
Condition: VEXAS Syndrome
Journal: Revue medicale suisse
Treatment Used: Azacitidine
Published: April 06, 2022
Summary: VEXAS syndrome : when do we have to consider it ?
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