Pyruvate Carboxylase Deficiency Latest Advances

Loss of Propionyl-CoA Carboxylase Reprograms Hepatic Metabolism by Suppressing Mitochondrial Pyruvate Carboxylation and Fatty Acid Oxidation.

Journal: bioRxiv : the preprint server for biology

Published: April 27, 2026

Holocarboxylase synthetase deficiency: pathogenesis, clinical features, diagnosis, treatment, and research prospects.

Journal: European journal of pediatrics

Published: November 03, 2025

Molecular mechanisms and targeted intervention strategies of renal tubular epithelial cell glycolytic reprogramming in renal fibrosis.

Journal: Life sciences

Published: October 08, 2025

Loss of pyruvate carboxylase suppresses lethality in propionic acidemia.

Journal: Cell reports

Published: October 06, 2025

Inhibiting pyruvate carboxylase as a potential therapeutic strategy for alleviating rheumatoid arthritis.

Journal: Inflammopharmacology

Published: September 14, 2025

Defects in ethanol fermentation catalysed by pyruvate decarboxylases reduce arsenic levels in rice.

Journal: Journal of experimental botany

Published: May 28, 2025

Clinical Efficacy and Safety of the Ketogenic Diet in Patients with Genetic Confirmation of Drug-Resistant Epilepsy.

Journal: Nutrients

Published: February 24, 2025

Case Report: Unusual Neurological Features of Leigh Syndrome due to m.8993T>G Pathogenic Variant in the MT-ATP6 Gene.

Journal: American journal of medical genetics. Part A

Published: February 10, 2025

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia-Inducible Factor-1 Signaling Pathway.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: December 18, 2024

Deletion of Pyruvate Carboxylase in Tubular Epithelial Cell Promotes Renal Fibrosis by Regulating SQOR/cGAS/STING-Mediated Glycolysis.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: July 28, 2024

Staphylococcal aconitase expression during iron deficiency is controlled by an sRNA-driven feedforward loop and moonlighting activity.

Journal: Nucleic acids research

Published: April 01, 2024

Chronic binge alcohol mediated hepatic metabolic adaptations in SIV-infected female rhesus macaques.

Journal: Alcohol and alcoholism (Oxford, Oxfordshire)

Published: March 01, 2024

Pyruvate Carboxylase Deficiency Latest Advances

Find the Latest Research About Pyruvate Carboxylase Deficiency

Loss of Propionyl-CoA Carboxylase Reprograms Hepatic Metabolism by Suppressing Mitochondrial Pyruvate Carboxylation and Fatty Acid Oxidation.

Loss of Propionyl-CoA Carboxylase Reprograms Hepatic Metabolism by Suppressing Mitochondrial Pyruvate Carboxylation and Fatty Acid Oxidation.

Holocarboxylase synthetase deficiency: pathogenesis, clinical features, diagnosis, treatment, and research prospects.

Holocarboxylase synthetase deficiency: pathogenesis, clinical features, diagnosis, treatment, and research prospects.

Molecular mechanisms and targeted intervention strategies of renal tubular epithelial cell glycolytic reprogramming in renal fibrosis.

Molecular mechanisms and targeted intervention strategies of renal tubular epithelial cell glycolytic reprogramming in renal fibrosis.

Loss of pyruvate carboxylase suppresses lethality in propionic acidemia.

Loss of pyruvate carboxylase suppresses lethality in propionic acidemia.

Inhibiting pyruvate carboxylase as a potential therapeutic strategy for alleviating rheumatoid arthritis.

Inhibiting pyruvate carboxylase as a potential therapeutic strategy for alleviating rheumatoid arthritis.

Defects in ethanol fermentation catalysed by pyruvate decarboxylases reduce arsenic levels in rice.

Defects in ethanol fermentation catalysed by pyruvate decarboxylases reduce arsenic levels in rice.

Clinical Efficacy and Safety of the Ketogenic Diet in Patients with Genetic Confirmation of Drug-Resistant Epilepsy.

Clinical Efficacy and Safety of the Ketogenic Diet in Patients with Genetic Confirmation of Drug-Resistant Epilepsy.

Case Report: Unusual Neurological Features of Leigh Syndrome due to m.8993T>G Pathogenic Variant in the MT-ATP6 Gene.

Case Report: Unusual Neurological Features of Leigh Syndrome due to m.8993T>G Pathogenic Variant in the MT-ATP6 Gene.

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia-Inducible Factor-1 Signaling Pathway.

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia-Inducible Factor-1 Signaling Pathway.

Deletion of Pyruvate Carboxylase in Tubular Epithelial Cell Promotes Renal Fibrosis by Regulating SQOR/cGAS/STING-Mediated Glycolysis.

Deletion of Pyruvate Carboxylase in Tubular Epithelial Cell Promotes Renal Fibrosis by Regulating SQOR/cGAS/STING-Mediated Glycolysis.

Staphylococcal aconitase expression during iron deficiency is controlled by an sRNA-driven feedforward loop and moonlighting activity.

Staphylococcal aconitase expression during iron deficiency is controlled by an sRNA-driven feedforward loop and moonlighting activity.

Chronic binge alcohol mediated hepatic metabolic adaptations in SIV-infected female rhesus macaques.

Chronic binge alcohol mediated hepatic metabolic adaptations in SIV-infected female rhesus macaques.