Condition 101 About Rasmussen Encephalitis

What is the definition of Rasmussen Encephalitis?

Rasmussen encephalitis is a chronic inflammatory neurological disease that usually affects only one hemisphere of the brain. It most often occurs in children under the age of 10, although adolescents and adults may also be affected. Rasmussen encephalitis is characterized by frequent and severe seizures, loss of motor skills and speech, paralysis on one side of the body (hemiparesis), inflammation of the brain (encephalitis), and mental deterioration. While the cause of Rasmussen encephalitis is unknown, there is evidence that in many patients it is an autoimmune disorder. Immune therapy and surgery may be used for treatment.

What are the alternative names for Rasmussen Encephalitis?

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What are the causes for Rasmussen Encephalitis?

The underlying cause of Rasmussen encephalitis remains unknown. Current evidence suggests that autoimmune processes are responsible for the damage to the brain cells. In most patients, the trigger of the abnormal immune response is unclear, although it may follow an otherwise minor bacterial or viral infection or head injury.  Rasmussen encephalitis is a sporadic disease. It has not been associated with any particular environments or populations and cannot be caught from others. Research is underway to help better understand the underlying cause.

What are the current treatments for Rasmussen Encephalitis?

Anti-epileptic drugs are usually not effective in controlling the seizures associated with Rasmussen encephalitis. Recent studies have shown some success with treatments that suppress or modulate the immune system, in particular those that use corticosteroids, intravenous immunoglobulin, or tacrolimus. Surgery to control seizures may be performed in later stages of the disease when neurological deficits stabilize. Surgical procedures, such as functional hemispherectomy (removal of half of the brain) and hemispherotomy (a surgical procedure for hemispheric disconnection), may reduce the frequency of seizures and also improve behavior and cognitive abilities.   

Top Global Doctors For Rasmussen Encephalitis

Kon H. Chu
Seoul, KR
Yukitoshi K. Takahashi
Shizuoka, JP
Annamaria Vezzani
Milan, IT
Sarosh R. Irani
Oxford, ENG, GB

Latest Advances On Rasmussen Encephalitis

  • Condition: anti-GABAB R Encephalitis
  • Journal: Medicine
  • Treatment Used: Etoposide with Immunotherapy
  • Number of Patients: 1
  • Published —
This case report describes a patient with anti-GABAB R encephalitis that was treated using etoposide and immunotherapy.
  • Condition: SARS-CoV-2-Related Mental Health Symptoms
  • Journal: Journal of psychiatric research
  • Treatment Used: Multidisciplinary Approach
  • Number of Patients: 0
  • Published —
This article discusses a neuroscience-based approach to reduce SARS-CoV-2 related mental health sequelae.

Clinical Trials For Rasmussen Encephalitis

Clinical Trial
  • Status: Recruiting
  • Intervention Type: Other
  • Participants: 30
  • Start Date: March 8, 2020
Description of neurolOgical Involvement Observed During SARS COV2 Infection
Clinical Trial
  • Status: Recruiting
  • Intervention Type: Other
  • Participants: 70
  • Start Date: January 22, 2020
Study of Neuro-ophthalmology Disorders in Autoimmune Encephalitis (NODE)