A Non-interventional Study Evaluating Clinical Utility and Implications on Improved Patient Management of Serum Neurofilament as a Prognostic Marker for Disease Activity in Patients With Relapsing Multiple Sclerosis (FILAXOS)
Status: Recruiting
Location: See all (104) locations...
Intervention Type: Other
Study Type: Observational
SUMMARY
This is a prospective, multicenter, observational, non-interventional study (NIS) in patients with Multiple Sclerosis (MS) and routinely assessed serum neurofilament light (sNfL) values in Germany
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 99
Healthy Volunteers: f
View:
⁃ Participants eligible for inclusion in this study must meet all the following criteria:
• Written informed consent must be obtained before participation in the study.
• RMS patients aged 18 or older.
• Treated in label with EU-approved DMTs for MS category 1 according to current guidelines (Hemmer et al 2023) for at least the last 3 months.
• Presence of a sNfL test result from a commercially available test not older than 3 months.
Locations
Other Locations
Germany
Novartis Investigative Site
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Aalen
Novartis Investigative Site
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Albstadt
Novartis Investigative Site
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Altenburg
Novartis Investigative Site
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Altenholz
Novartis Investigative Site
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Aschaffenburg
Novartis Investigative Site
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Augsburg
Novartis Investigative Site
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Backnang
Novartis Investigative Site
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Bad Homburg
Novartis Investigative Site
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Bad Krozingen
Novartis Investigative Site
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Bamberg
Novartis Investigative Site
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Bergneustadt
Novartis Investigative Site
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Berlin
Novartis Investigative Site
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Berlin
Novartis Investigative Site
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Berlin
Novartis Investigative Site
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Berlin
Novartis Investigative Site
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Berlin
Novartis Investigative Site
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Berlin
Novartis Investigative Site
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Bielefeld
Novartis Investigative Site
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Bochum
Novartis Investigative Site
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Bogen
Novartis Investigative Site
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Bonn
Novartis Investigative Site
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Chemnitz
Novartis Investigative Site
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Coburg
Novartis Investigative Site
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Dessau
Novartis Investigative Site
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Dillingen Saar
Novartis Investigative Site
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Dortmund
Novartis Investigative Site
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Dortmund
Novartis Investigative Site
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Dresden
Novartis Investigative Site
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Dresden
Novartis Investigative Site
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Duisburg
Novartis Investigative Site
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Düsseldorf
Novartis Investigative Site
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Düsseldorf
Novartis Investigative Site
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Düsseldorf
Novartis Investigative Site
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Eisleben Lutherstadt
Novartis Investigative Site
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Eltville
Novartis Investigative Site
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Erbach Im Odenwald
Novartis Investigative Site
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Erfurt
Novartis Investigative Site
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Essen
Novartis Investigative Site
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Essen
Novartis Investigative Site
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Frankfurt Am Main
Novartis Investigative Site
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Frankfurt Am Main
Novartis Investigative Site
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Gelsenkirchen
Novartis Investigative Site
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Gelsenkirchen
Novartis Investigative Site
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Gera
Novartis Investigative Site
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Görlitz
Novartis Investigative Site
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Göttingen
Novartis Investigative Site
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Hagen
Novartis Investigative Site
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Hamburg
Novartis Investigative Site
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Hamburg
Novartis Investigative Site
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Hanover
Novartis Investigative Site
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Heidenheim
Novartis Investigative Site
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Herford
Novartis Investigative Site
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Hettingen
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Hoppegarten
Novartis Investigative Site
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Höxter
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Itzehoe
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Jena
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Karlsruhe
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Kassel
Novartis Investigative Site
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Katzenelnbogen
Novartis Investigative Site
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Leipzig
Novartis Investigative Site
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Leipzig
Novartis Investigative Site
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Leipzig
Novartis Investigative Site
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Lüneburg
Novartis Investigative Site
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Magdeburg
Novartis Investigative Site
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Magdeburg
Novartis Investigative Site
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Mannheim
Novartis Investigative Site
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Meerbusch
Novartis Investigative Site
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Merzig
Novartis Investigative Site
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Minden
Novartis Investigative Site
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Mühlhausen
Novartis Investigative Site
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München
Novartis Investigative Site
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München
Novartis Investigative Site
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Neuburg An Der Donau
Novartis Investigative Site
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Neuwied
Novartis Investigative Site
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Osnabrück
Novartis Investigative Site
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Pforzheim
Novartis Investigative Site
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Quakenbrück
Novartis Investigative Site
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Regensburg
Novartis Investigative Site
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Remscheid
Novartis Investigative Site
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Rülzheim
Novartis Investigative Site
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Salzatal
Novartis Investigative Site
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Schiltach
Novartis Investigative Site
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Schwäbisch Hall
Novartis Investigative Site
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Schwalmstadt-treysa
Novartis Investigative Site
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Schwetzingen
Novartis Investigative Site
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Siegen
Novartis Investigative Site
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Siegen
Novartis Investigative Site
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Singen
Novartis Investigative Site
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Sinsheim
Novartis Investigative Site
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Stadtroda
Novartis Investigative Site
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Stuttgart
Novartis Investigative Site
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Stuttgart
Novartis Investigative Site
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Sundern Hachen
Novartis Investigative Site
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Tirschenreuth
Novartis Investigative Site
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Ulm
Novartis Investigative Site
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Unterhaching
Novartis Investigative Site
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Untermeiting
Novartis Investigative Site
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Velbert
Novartis Investigative Site
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Weiden
Novartis Investigative Site
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Weil Der Stadt
Novartis Investigative Site
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Witten
Novartis Investigative Site
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Wolfenbüttel
Novartis Investigative Site
WITHDRAWN
Wolfratshausen
Contact Information
Primary
Novartis Pharmaceuticals
novartis.email@novartis.com
+41613241111
Backup
Novartis Pharmaceuticals
Time Frame
Start Date: 2024-10-23
Estimated Completion Date: 2028-11-29
Participants
Target number of participants: 900
Treatments
Ofatumumab
Patients who have received treatment with category 1 DMTs and decided to switch to ofatumumab
Category 1 DMTs
Patients who continued with DMT category 1 treatment. According to local treatment guidelines, DMT category 1 include dimethylfumarate/diroximelfumarate, glatirameroids, Interferon beta and teriflunomide.
Related Therapeutic Areas
Sponsors
Leads: Novartis Pharmaceuticals