Condition 101 About Renal Glycosuria

What is the definition of Renal Glycosuria?

Renal glycosuria is a rare condition in which glucose is excreted in the urine despite normal or low blood glucose levels. With normal kidney function, glucose is excreted in the urine only when there are abnormally elevated levels of glucose in the blood. However, in people with renal glycosuria, glucose is abnormally eliminated in the urine due to improper functioning of the renal tubules, which are the primary components of the filtering units of the kidneys. In most people with renal glycosuria, there are no apparent symptoms or serious effects. Rare cases of polyuria (increased urine output), enuresis (involuntary urination), and mild delays in growth and maturation during puberty have been reported. When renal glycosuria occurs as an isolated finding with otherwise normal kidney function, the condition is thought to be caused by mutations in the SLC5A2 gene. Treatment is not typically needed.

What are the alternative names for Renal Glycosuria?

  • Renal glucosuria

What are the current treatments for Renal Glycosuria?

In most affected individuals, no treatment is required. However, some individuals with renal glycosuria may develop diabetes mellitus. Therefore, appropriate testing should be conducted to rule out diabetes and to regularly monitor those with confirmed renal glycosuria.

Top Global Doctors For Renal Glycosuria

JC
Elite
Joaquim T. Calado
Lisbon, PT
LY
Elite
Lei Yu
Hohhot, CN
PH
Distinguished
Ping Hou
Beijing, CN
IA
Distinguished
Ines D. Aires
Coimbra, PT

Latest Advances On Renal Glycosuria

  • Condition: Nonalcoholic Steatohepatitis In Patients With Type 2 Diabetes Mellitus
  • Journal: Digestive diseases and sciences
  • Treatment Used: Empagliflozin
  • Number of Patients: 9
  • Published —
The purpose of the study was to explore whether Empagliflozin added to the usual care for patients with type 2 diabetes mellitus and biopsy-proven nonalcoholic steatohepatitis will benefit nonalcoholic steatohepatitis histology.

Clinical Trials For Renal Glycosuria

Clinical Trial
  • Status: Recruiting
  • Intervention Type: Other
  • Participants: 10
  • Start Date: January 24, 2019
Human SLC5A2 Deficiency and the Glucagon-Incretin Axis: A Pilot Study