Retroperitoneal inflammation causes swelling that occurs in the retroperitoneal space. Over time, it can lead to a mass behind the abdomen called retroperitoneal fibrosis.
The retroperitoneal space is in front of the lower back and behind the abdominal lining (peritoneum). Organs in this space include the:
Retroperitoneal inflammation and fibrosis is a rare condition. There is no clear cause in about 70% of cases. It most likely develops due to inflammation of the abdominal aortic artery.
Conditions that can rarely lead to this include:
Treatment depends on the underlying cause of retroperitoneal inflammation and fibrosis.
How well you do with the condition depends on the underlying cause. It can lead to kidney failure.
Published Date: October 11, 2020
Published By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
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