Learn About Retroperitoneal Inflammation
Retroperitoneal inflammation causes swelling that occurs in the retroperitoneal space. Over time, it can lead to a mass behind the abdomen and its contents called retroperitoneal fibrosis.
The retroperitoneal space is in front of the lower back and behind the abdominal lining (peritoneum). Organs in this space include the:
- Kidneys
- Lymph nodes
- Pancreas
- Ureters
- Adrenal glands
- Esophagus
- Abdominal aorta
- Parts of the colon and stomach
- Rectum
Retroperitonitis
Retroperitoneal inflammation and fibrosis is a rare condition. There is no clear cause in about 70% of cases. It most likely develops due to inflammation of the abdominal aortic artery.
It has been associated with certain risk factors and medicines.
Conditions that can rarely lead to this include:
- Abdominal radiation therapy for cancer
- Cancer -- bladder, breast, colon, lymphoma, prostate, sarcoma
- Carcinoid tumor
- Crohn disease
- Infections -- tuberculosis, histoplasmosis
- Certain medicines, such as methysergide, ergotamine, pergolide, methyldopa, etanercept and infliximab
- Surgery on structures in the retroperitoneum
Symptoms include:
- Abdominal pain
- Anorexia
- Flank pain
- Low back pain
- Malaise
Treatment depends on the underlying cause of retroperitoneal inflammation and fibrosis.
Advocate Medical Group General Surgery
Marin Marinov is a General Surgeon in Park Ridge, Illinois. Dr. Marinov is rated as a Distinguished provider by MediFind in the treatment of Retroperitoneal Inflammation. His top areas of expertise are Retroperitoneal Inflammation, Delirium, Gallbladder Disease, Hernia Surgery, and Colostomy.
Lila Oyama practices in Sao Paulo, Brazil. Ms. Oyama is rated as an Elite expert by MediFind in the treatment of Retroperitoneal Inflammation. Her top areas of expertise are Obesity, Retroperitoneal Inflammation, Obesity in Children, Oophorectomy, and Hormone Replacement Therapy (HRT).
Christiana Care Health Services Inc
Nikolay Mindadze is a General Surgeon in Wilmington, Delaware. Dr. Mindadze is rated as a Distinguished provider by MediFind in the treatment of Retroperitoneal Inflammation. His top areas of expertise are Retroperitoneal Inflammation, Gallbladder Disease, Ogilvie Syndrome, Gallstones, and Hernia Surgery. Dr. Mindadze is currently accepting new patients.
How well you do with the condition depends on the underlying cause. It can lead to kidney failure.
Published Date: October 27, 2024
Published By: Laura J. Martin, MD, MPH, ABIM Board Certified in Internal Medicine and Hospice and Palliative Medicine, Atlanta, GA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Mathews JB, Turaga K. Surgical peritonitis and other diseases of the peritoneum, mesentery, omentum, and diaphragm. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 11th ed. Philadelphia, PA: Elsevier; 2021:chap 39.
McQuaid KR. Approach to the patient with gastrointestinal disease. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 118.
Privratsky AM, Barreto JC, Turnage RH. Abdominal wall, umbilicus, peritoneum, mesenteries, omentum, and retroperitoneum. In: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Textbook of Surgery. 21st ed. Philadelphia, PA: Elsevier; 2022:chap 44.