Rhabdoid Tumor
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Learn About Rhabdoid Tumor

What is the definition of Rhabdoid Tumor?
Rhabdoid tumor (RT) is an aggressive pediatric soft tissue sarcoma that arises in the kidney, the liver, the peripheral nerves and all miscellaneous soft-parts throughout the body. RT involving the central nervous system (CNS) is called atypical teratoid Rhabdoid tumor. RT usually occurs in infancy or childhood. In most cases, the first symptoms are linked to the compressive effects of a bulky tumor (such as respiratory distress, abdominal mass, peripheral nerve palsy). In about 90% of cases it is caused by a genetic change in the SMARCB1 gene, which is a tumor suppressor gene. In rare cases, it may be caused by a genetic change in the SMARCA4 gene. No standard care exists for RT, although there are many ongoing studies.
What are the alternative names for Rhabdoid Tumor?
  • Rhabdoid tumor
  • Atypical teratoid rhabdoid tumor
  • BRAIN TUMOR, POSTERIOR FOSSA, OF INFANCY, FAMILIAL
  • Malignant rhabdoid tumor
  • RHABDOID TUMOR PREDISPOSITION SYNDROME 1
  • Rhabdoid sarcoma
  • Rhabdoid tumor predisposition syndrome 2
Who are the top Rhabdoid Tumor Local Doctors?
Eric Raabe
Elite in Rhabdoid Tumor
Oncology | Pediatrics
Elite in Rhabdoid Tumor
Oncology | Pediatrics

Johns Hopkins Children's Center

Baltimore, MD 
Languages Spoken:
English, French

Eric Raabe, M.D., Ph.D., is an associate professor of oncology and pathology at Johns Hopkins School of Medicine. Dr. Raabe majored in neural science at Brown University and received his M.D. and Ph.D. from the University of Cincinnati College of Medicine. He completed his pediatric internship and residency at Children’s Hospital of Philadelphia. After spending a year working in Africa as part of the Baylor International Pediatric AIDS Initiative, Dr. Raabe joined Johns Hopkins as a pediatric oncology fellow. Working in the laboratory of Charles Eberhart in Neuropathology, Dr. Raabe established a neural stem cell system to create genetically accurate models of pediatric brain tumors. In collaboration with patients and families, he has also developed multiple pediatric brain tumor cell lines that are some of the key models used for pre-clinical testing. Dr. Raabe sees patients in the pediatric oncology outpatient clinic at Johns Hopkins, with a focus on pediatric brain tumors. Dr. Raabe is also the point person in oncology for retinoblastoma care. He continues his research in the new Smith Building of the Wilmer Eye Institute in the Neuropathology Division, in collaboration with Charles Eberhart. Dr. Raabe is rated as an Elite provider by MediFind in the treatment of Rhabdoid Tumor. His top areas of expertise are Rhabdoid Tumor, Diffuse Midline Glioma H3 K27M-Mutant, Glioma, and Medulloblastoma.

Pamela E. Kaiser
Advanced in Rhabdoid Tumor
Hematology | Oncology
Advanced in Rhabdoid Tumor
Hematology | Oncology

Advocate Lutheran General Cancer Institute

1700 Luther Ln 1st & 2nd Fl, 
Park Ridge, IL 
Languages Spoken:
English

Pamela Kaiser is a Hematologist and an Oncologist in Park Ridge, Illinois. Dr. Kaiser is rated as an Advanced provider by MediFind in the treatment of Rhabdoid Tumor. Her top areas of expertise are Angiosarcoma, Breast Cancer, Paget Disease of the Breast, Inflammatory Breast Cancer, and Endoscopy.

 
 
 
 
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Nicholas P. Webber
Advanced in Rhabdoid Tumor
Advanced in Rhabdoid Tumor

Aurora Orthopedics

2801 W Kinnickinnic River Pkwy, Ste 370, 
Milwaukee, WI 
Languages Spoken:
English

Nicholas Webber is an Orthopedics provider in Milwaukee, Wisconsin. Dr. Webber is rated as an Advanced provider by MediFind in the treatment of Rhabdoid Tumor. His top areas of expertise are Osteoarthritis, Osteonecrosis, Rhabdomyosarcoma Embryonal, Hip Replacement, and Knee Replacement.

What are the latest Rhabdoid Tumor Clinical Trials?
A Randomized Phase I/II Study of Talazoparib or Temozolomide in Combination With Onivyde in Children With Recurrent Solid Malignancies and Ewing Sarcoma

Summary: The phase I portion of this study is designed for children or adolescents and young adults (AYA) with a diagnosis of a solid tumor that has recurred (come back after treatment) or is refractory (never completely went away). The trial will test 2 combinations of therapy and participants will be randomly assigned to either Arm A or Arm B. The purpose of the phase I study is to determine the highest ...

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A Multicenter, Open-label, Uncontrolled Phase II Study to Investigate Efficacy and Safety of ONO4538 in Patients With Rhabdoid Tumor

Summary: Investigate the efficacy and safety of ONO-4538 for the treatment of rhabdoid Tumors

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Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center