Use of Sodium Bicarbonate As Prophylaxis for Kidney Damage in Patients with Heatstroke
Status: Recruiting
Location: See location...
Intervention Type: Drug, Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study protocol aims to prevent the need for renal replacement therapy in patients with rhabdomyolysis secondary to heatstroke. It is based on previous studies showing that bicarbonate infusion reduces renal failure in similar contexts. The intervention will be conducted at the General Hospital of Mexicali during the summer, targeting the prevention of renal failure and reducing the necessity for renal replacement therapy.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:
• Admitted to the General Hospital of Mexicali with the diagnosis of heat stroke.
• Meeting the operational definition (exposure to heat, body temperature at admission greater than 40 degrees Celsius).
• CPK level greater than 1000 U/L.
• Having informed consent from the patient or the legally responsible adult.
Locations
Other Locations
Mexico
Hospital General de Mexicali
RECRUITING
Mexicali
Contact Information
Primary
Joaquin Cordova Erberk, MD
joaquincerberk@gmail.com
+52 653 132 0309
Backup
Hiram J Jaramillo Ramirez, MD
grupoinvestigacionmedica@gmail.com
+52 653 132 0309
Time Frame
Start Date: 2024-05-01
Estimated Completion Date: 2025-10-01
Participants
Target number of participants: 1
Treatments
Experimental: Intervention Group
This group will receive 100 mEq of sodium bicarbonate diluted in one liter of saline solution, administered at a rate of 100 ml/h, with the goal of maintaining a urinary pH greater than 6.5.
Active_comparator: Control Group
This group will be manage with the usual care that is given to patients with heat stroke in this hospital.
Related Therapeutic Areas
Sponsors
Leads: Hospital General de Mexicali
Collaborators: Universidad Autonoma de Baja California