Investigation of the Effects of a Gluten-Free Diet and the Mediterranean Diet on the Inflammatory Index, Disease Activity, and Quality of Life in Patients With Rheumatoid Arthritis.
Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study aims to evaluate the effects of different dietary interventions, including gluten-free, Mediterranean, and control diets, on disease activity, quality of life, and dietary inflammatory index in patients with rheumatoid arthritis. Participants will be followed for 12 weeks, and changes in clinical and nutritional outcomes will be assessed.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 19
Maximum Age: 65
Healthy Volunteers: f
View:
• Diagnosis of rheumatoid arthritis according to ACR/EULAR criteria Age between 19-65 years Stable medication regimen for at least 3 months prior to enrollment Willingness to comply with dietary interventions and study procedures Ability to provide informed consent
Locations
Other Locations
Turkey
NCR International Hospital
RECRUITING
Gaziantep
Contact Information
Primary
Nilüfer Gürsel, PhD
nilufergursell@gmail.com
+90 506 379 73 42
Backup
Mine Yurttagül, Prof. Dr.
mine@yurttagul.com
Time Frame
Start Date: 2025-10-29
Estimated Completion Date: 2026-08-31
Participants
Target number of participants: 66
Treatments
Experimental: Gluten-Free Diet Group
Participants will follow a gluten-free diet for 12 weeks. All gluten-containing foods will be eliminated, and dietary guidance will be provided throughout the intervention period.
Experimental: Mediterranean Diet Group
Participants will follow a Mediterranean diet for 12 weeks, emphasizing high intake of fruits, vegetables, whole grains, legumes, olive oil, and fish, with limited processed foods.
Active_comparator: Control Diet Group
Participants will continue their usual diet without specific dietary modifications. General dietary advice may be provided but no structured intervention will be implemented.
Related Therapeutic Areas
Sponsors
Leads: Hasan Kalyoncu University