Comparative Effectiveness of Different Drugs Used to Treat Patients in Rheumatoid Arthritis Saudi Database (RASD) The Primary Objective of This Study is to Compare the Effectiveness of Different Biological Disease Modifying Antirheumatic Drugs (bDMARDs) and Targeted Synthetic (tsDMARDs) Using DAS-28-CRP and CDAI Scores.

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

Comparative effectiveness of different drugs used to treat patients in Rheumatoid Arthritis Saudi database (RASD) The goal of this observational study is to compare the effectiveness of different biological Disease Modifying Antirheumatic Drugs (bDMARDs) and targeted synthetic (tsDMARDs) using Disease Activity Score - 28 joints - C-Reactive Protien (DAS-28-CRP) and Clinical Disease Activity Index (CDAI) scores. In rheumatoid arthritis patients in Saudi Arabia who are part of Rheumatoid Arthritis Saudi Database (RASD). The main question\[s\] it aims to answer: * What is the most effective drug (biologocal or targeted synthetic) disease modifying antirheumatic drug used to treat rheumatoid arthritis in Saudi Arabia? * We are going to use two outcome mesures: Disease Activity Score - 28 joints - C-Reactive Protien (DAS-28-CRP) and Clinical Disease Activity Index (CDAI) scores Researchers will compare the treatment of rheumatoid arthritis using specific outcome measures in Rheumatoid Arthritis in Saudi Arabia. * Participants will be enrolled after a signed written concent in our Rheumatoid Arthritis Saudi Databas (RASD). * Their treatment data will used to compare the effectiveness of different drugs they are using.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• All those patients who are age of 18 years and above and

• meeting 2010 American College of Rheumatology classification criteria for rheumatoid arthritis.

• Both male and female gender will be included.

• There should be minimum of 12 months follow up with at least 3 documented visits of these patients to health care facilities.

Locations
Other Locations
Saudi Arabia
International medical center
RECRUITING
Jeddah
Contact Information
Primary
Hani Almoallim, Professor of Rheumatology
hmmoallim@uqu.edu.sa
00966+505703935
Backup
Suzan Attar, Professor of Rheumatology
suzan_attar@hotmail.com
00966+562222613
Time Frame
Start Date: 2023-12-15
Estimated Completion Date: 2025-03-15
Participants
Target number of participants: 800
Treatments
Rheumatoid arthritis patients receiving biological DMARDs or targeted synthetic DMARDs
It will be a multicenter study. The data will be obtained primarily from Rheumatoid Arthritis Saudi Database (RASD). We will also include RA patients from other centers who are not part of the registry if they are providing minimum of 12 months follow up with at least 3 documented visits of these patients to health care facilities following treat to target approach or preferably treat to work approach.
Related Therapeutic Areas
Sponsors
Leads: Umm Al-Qura University

This content was sourced from clinicaltrials.gov