Einfluss Ballaststoffreicher Ernährung Auf Das Mikrobiom Und Die Krankheitsaktivität Von Patientinnen Und Patienten Mit Rheumatoider Arthritis

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to learn if increasing dietary fiber can improve the gut microbiome and reduce disease activity in adults with rheumatoid arthritis (RA). The main questions it aims to answer are: * Can a higher fiber diet improve gut bacteria and produce beneficial short-chain fatty acids (SCFAs)? * Does a higher fiber diet reduce RA symptoms and help with weight loss? Researchers will compare two groups: one group will receive dietary counseling and take 10 grams of psyllium husk daily, while the other group will continue their usual diet. Participants will: * Complete dietary questionnaires at the start, 6 months, and 12 months. * Provide stool samples for gut bacteria and SCFA analysis. * Have their RA activity and body weight monitored regularly. * Receive regular phone calls to support the dietary changes. The study will involve adults with diagnosed RA who can provide informed consent and meet other inclusion criteria.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 99
Healthy Volunteers: f
View:

• Patients over 18 years old

• Diagnosis of Rheumatoid Arthritis according to the ACR criteria of 2010

• The patient can understand the scope of the study and consents in writing to participate.

Locations
Other Locations
Germany
University Würzburg
RECRUITING
Würzburg
Contact Information
Primary
Eva C Schwaneck, M.D.
e.schwaneck@rheuma-hh.de
+49 40 1818 81 8343
Backup
Michael Gernert, M.D.
gernert_m1@ukw.de
+49 931 201 40 100
Time Frame
Start Date: 2024-06-01
Estimated Completion Date: 2026-12-30
Participants
Target number of participants: 52
Treatments
Experimental: Intervention Group
No_intervention: Control Group
Related Therapeutic Areas
Sponsors
Collaborators: RheinNatur Food GmbH
Leads: Wuerzburg University Hospital

This content was sourced from clinicaltrials.gov