Development and Validation of a Deprescribing Tool Relevant to the Indian Context and Evaluation of Its Effectiveness in Reducing Inappropriate Polypharmacy in the Elderly

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to learn if a deprescribing tool can help in reducing prescriptions with potentially inappropriate medications (PIMs), in the Indian elderly population. The main question it aims to answer is- Can inappropriate polypharmacy in elderly patients be reduced through development and implementation of a deprescribing tool relevant to the Indian context? Researchers will compare control arm outcome parameters to see if there is a reduction in Proportion of prescriptions with at least one PIM ( Primary outcome parameter). Participating Prescribers ( Physicians) will be randomized to Control or Intervention arms. Particpating patients will not be randomized, and will receive routine consultation with a Physician who does not use the Deprescribing Tool (Control arm) or a prescriber who uses the Deprescribing tool ( Intervention Arm)

Eligibility
Participation Requirements
Sex: All
Minimum Age: 60
Healthy Volunteers: f
View:

• Elderly patients (≥ 60 years) of either sex, visiting the General Medicine/ Community and Family Medicine OPD of the study sites

Locations
Other Locations
India
St. John's Medical College, Bangalore, India
RECRUITING
Bangalore
All India Institute of Medical Sciences Bhopal
RECRUITING
Bhopal
Contact Information
Primary
Ratinder Jhaj, DM
rati.pharm@aiimsbhopal.edu.in
+917773002096
Backup
Dr. Atiya Faruqui, MD
atiya.rf@stjohns.in
+91 9980018022
Time Frame
Start Date: 2025-05-01
Estimated Completion Date: 2026-09
Participants
Target number of participants: 1650
Treatments
No_intervention: Control Arm
Prescribers in this arm will not use the Deprescribing Tool, and will prescribe as per routine practice.
Experimental: Intervention Arm
Prescribers in this arm will be trained in the use of the Deprescribing Tool and provided the Tool for medication review during patient consultation. The prescriber will be encouraged to refer to the tool for medication review of elderly patients aged ≥ 60 years and take deprescribing decision if indicated.
Related Therapeutic Areas
Sponsors
Collaborators: St Johns Medical College Hospital, Bangalore, India
Leads: Indian Council of Medical Research

This content was sourced from clinicaltrials.gov