Learn About Ribbing Disease

What is the definition of Ribbing Disease?
Ribbing disease is a rare disease that causes bony growths to develop on the long bones. These bony growths most commonly affect the long bones of the lower legs, such as the thigh bone (femur) and shin bone (tibia) but can also affect the long bones of the arms. Signs and symptoms of the disease may include pain and muscle weakness in the areas where the bone growths are occurring. The bone growths typically occur only on one side of the body or in different bones on both sides of the body. These symptoms most commonly begin during adulthood, typically when a person is around 30-years-old. Ribbing disease has similar signs and symptoms to another disease called Camurati-Engelmann disease (CED). However, symptoms of CED typically begin at a younger age and may affect more bones on both sides of the body than Ribbing disease does. The exact cause of Ribbing disease is currently unknown. Some researchers think that Ribbing disease is caused by genetic changes (pathogenic variants or mutations) in the TGFB1 gene, and that the disease is inherited in an autosomal recessive manner. Diagnosis of Ribbing disease is based on observing signs and symptoms of the disease such as bone pain, especially in the bones of the legs. The diagnosis can be confirmed with procedures that help visualize the bones in the body including CT scan, MRI, and bone scan. Treatment options for Ribbing disease may include medications such as non-steroidal anti-inflammatory drugs (NSAIDS), bisphosphonate, and prednisone. If medications do not help resolve the symptoms of Ribbing disease, a surgical procedure called intramedullary reaming may be recommended.
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What are the alternative names for Ribbing Disease?
  • Multiple diaphyseal sclerosis
  • Diaphyseal sclerosis, multiple
  • Hereditary multiple diaphyseal sclerosis
Who are the top Ribbing Disease Local Doctors?
Distinguished
Highly rated in
3
conditions
Podiatric Medicine

Rosemarie Caillier DPM PC

Tuscaloosa, AL 

Rosemarie Caillier is a Podiatric Medicine doctor in Tuscaloosa, Alabama. Dr. Caillier has been practicing medicine for over 25 years and is rated as a Distinguished doctor by MediFind in the treatment of Ribbing Disease. She is also highly rated in 3 other conditions, according to our data. Her top areas of expertise are Ribbing Disease, Camurati-Engelmann Disease, Ghosal Hematodiaphyseal Dysplasia, and Type 2 Diabetes. She is board certified in Podiatry and licensed to treat patients in Louisiana and Alabama. Dr. Caillier is currently accepting new patients.

Advanced
Highly rated in
8
conditions
Addiction Medicine

Azalea Internal Medicine Associates

Tyler, TX 

Neil Adelman is an Addiction Medicine doctor in Tyler, Texas. Dr. Adelman has been practicing medicine for over 44 years and is rated as an Advanced doctor by MediFind in the treatment of Ribbing Disease. He is also highly rated in 8 other conditions, according to our data. His top areas of expertise are Scoliosis, Sciatica, Chronic Pain, and Ribbing Disease. He is board certified in Internal Medicine and Addiction Medicine and licensed to treat patients in Texas. Dr. Adelman is currently accepting new patients.

 
 
 
 
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Advanced
Highly rated in
32
conditions
Orthopedics

Baylor Scott & White Medical Center - Temple

Temple, TX 

Russell Ward is an Orthopedics doctor in Temple, Texas. Dr. Ward has been practicing medicine for over 19 years and is rated as an Advanced doctor by MediFind in the treatment of Ribbing Disease. He is also highly rated in 32 other conditions, according to our data. His top areas of expertise are Liposarcoma, Bone Tumor, Malignant Mesenchymoma, and Undifferentiated Pleomorphic Sarcoma. He is board certified in Orthopedic Surgery and licensed to treat patients in Texas. Dr. Ward is currently accepting new patients.

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What are the Latest Advances for Ribbing Disease?

There is no recent research available for this condition. Please check back because thousands of new papers are published every week and we strive to find and display the most recent relevant research as soon as it is available.