RoseolaSymptoms, Doctors, Treatments, Advances & More
Learn About Roseola
Roseola is a viral infection that commonly affects infants and young children. It involves a pinkish-red skin rash and high fever.
Exanthem subitum; Sixth disease
Roseola is common in children ages 3 months to 4 years, and most common in those ages 6 months to 1 year.
It is caused by a virus called human herpesvirus 6 (HHV-6), although similar syndromes are possible with other viruses.
The time between becoming infected and the beginning of symptoms (incubation period) is 5 to 15 days.
The first symptoms include:
- Eye redness
- Irritability
- Runny nose
- Sore throat
- High fever, that comes on quickly and may be as high as 105°F (40.5°C) and can last 3 to 7 days
About 2 to 4 days after becoming sick, your child's fever lowers and a rash appears. This rash most often:
- Starts on the middle of the body and spreads to the arms, legs, neck, and face
- Is pink or rose-colored
- Has small sores that are slightly raised
The rash lasts from a few hours to 2 to 3 days. It usually does not itch.
There is no specific treatment for roseola. The disease most often gets better on its own without complications.
Acetaminophen (Tylenol) and cool sponge baths can help reduce the fever. Some children may have seizures when they get a high fever. If this occurs, call your provider or go to the closest emergency room.
Yutao Guo practices in Haidian, China. Guo is rated as an Elite expert by MediFind in the treatment of Roseola. Their top areas of expertise are Roseola, Atrial Fibrillation, Stroke, and Venous Thromboembolism (VTE).
Hiroki Miura practices in Toyoake, Japan. Mr. Miura is rated as an Elite expert by MediFind in the treatment of Roseola. His top areas of expertise are Roseola, Chickenpox, X-Linked Severe Combined Immunodeficiency, Bone Marrow Transplant, and Bone Marrow Aspiration.
Bassett Medical Center
. Dr. Szyikowski is rated as an Experienced provider by MediFind in the treatment of Roseola. His top areas of expertise are Obesity in Children, Developmental Dysphasia Familial, Adie Syndrome, and Scarlet Fever.
Complications may include:
- Aseptic meningitis (rare)
- Encephalitis (rare)
- Febrile seizure
Contact your provider if your child:
- Has a fever that does not go down with the use of acetaminophen (Tylenol) or ibuprofen (Advil) and a cool bath
- Continues to appear very sick
- Is irritable or seems extremely tired
Go to the emergency room or call the local emergency number (such as 911) if your child has convulsions.
Careful handwashing can help prevent the spread of the viruses that cause roseola.
Published Date: July 01, 2025
Published By: Charles I. Schwartz, MD, FAAP, Clinical Assistant Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, General Pediatrician at PennCare for Kids, Phoenixville, PA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Cherry J, Doustmohammadi S. Roseola infantum (exanthem subitum). In: Cherry JD, Kaplan SL, Harrison GJ, Steinbach WJ, Hotez PJ, Williams JV, eds. Feigin and Cherry's Textbook of Pediatric Infectious Diseases. 9th ed. Philadelphia, PA: Elsevier; 2025:chap 61.
Michaels MG, Williams JV. Infectious diseases. In: Zitelli BJ, McIntire SC, Nowalk AJ, Garrison J, eds. Zitelli and Davis' Atlas of Pediatric Physical Diagnosis. 8th ed. Philadelphia, PA: Elsevier; 2023:chap 13.
Tesini BL. Roseola (human herpesviruses 6 and 7). In: Kliegman RM, St. Geme JW, Blum NJ, et al, eds. Nelson Textbook of Pediatrics. 22nd ed. Philadelphia, PA: Elsevier; 2025:chap 303.