Learn About Salivary Gland Tumors

What is the definition of Salivary Gland Tumors?

Salivary gland tumors are abnormal cells growing in the gland or in the tubes (ducts) that drain the salivary glands.

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What are the alternative names for Salivary Gland Tumors?

Tumor - salivary duct

What are the causes of Salivary Gland Tumors?

The salivary glands are located around the mouth. They produce saliva, which moistens food to help with chewing and swallowing. Saliva also helps to protect teeth from decay.

There are 3 main pairs of salivary glands. The parotid glands are the largest. They are located in each cheek in front of the ears. Two submandibular glands are under the floor of the mouth under both sides of the jaw. Two sublingual glands are under the floor of the mouth. There are also hundreds of small salivary glands lining the rest of the mouth. These are called the minor salivary glands.

Salivary glands empty saliva into the mouth through ducts that open at various places in the mouth.

Salivary gland tumors are rare. Swelling of the salivary glands is mostly due to:

  • Major abdominal and hip repair surgeries
  • Cirrhosis of the liver
  • Infections
  • Other cancers
  • Salivary duct stones
  • Salivary gland infections
  • Dehydration
  • Sarcoidosis
  • Sjögren syndrome

The most common type of salivary gland tumor is a slow-growing noncancerous (benign) tumor of the parotid gland. The tumor gradually increases the size of the gland. Some of these tumors can be cancerous (malignant).

What are the symptoms of Salivary Gland Tumors?

Symptoms may include any of the following:

  • Firm, usually painless swelling in one of the salivary glands (in front of the ears, under the chin, or on the floor of the mouth). The swelling gradually increases.
  • Difficulty moving one side of the face, known as facial nerve palsy.
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What are the current treatments for Salivary Gland Tumors?

Surgery is most often done to remove the affected salivary gland. If the tumor is benign, no other treatment is needed.

Radiation therapy or extensive surgery may be needed if the tumor is cancerous. Chemotherapy may be used when the disease has spread beyond the salivary glands.

Who are the top Salivary Gland Tumors Local Doctors?
Elite
Highly rated in
34
conditions
Otolaryngology

Memorial Sloan Kettering Cancer Center

1275 York Ave 
New York, NY 10065

Ian Ganly is an Otolaryngologist in New York, New York. Dr. Ganly has been practicing medicine for over 33 years and is rated as an Elite doctor by MediFind in the treatment of Salivary Gland Tumors. He is also highly rated in 34 other conditions, according to our data. His top areas of expertise are Thyroid Cancer, Anaplastic Thyroid Cancer, Salivary Gland Tumors, and Tongue Cancer. He is board certified in Otolaryngology and licensed to treat patients in New York. Dr. Ganly is currently accepting new patients.

Elite
Highly rated in
38
conditions
Otolaryngology
Surgical Oncology
General Surgery

University of Texas System

Physicians Referral Service

1515 Holcombe Blvd 
Houston, TX 77030

Ehab Hanna is an Otolaryngologist and a Surgical Oncologist in Houston, Texas. Dr. Hanna has been practicing medicine for over 40 years and is rated as an Elite doctor by MediFind in the treatment of Salivary Gland Tumors. He is also highly rated in 38 other conditions, according to our data. His top areas of expertise are Sinus Cancer, Olfactory Neuroblastoma, Adenoid Cystic Carcinoma, and Salivary Gland Tumors. He is board certified in Otolaryngology and Surgical Oncology and licensed to treat patients in Texas. Dr. Hanna is currently accepting new patients.

 
 
 
 
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Elite
Highly rated in
31
conditions
Otolaryngology

Penn Medicine

Perelman Center For Advanced Medicine

3400 Civic Center Blvd 
Philadelphia, PA 19104

Gregory Weinstein is an Otolaryngologist in Philadelphia, Pennsylvania. Dr. Weinstein has been practicing medicine for over 37 years and is rated as an Elite doctor by MediFind in the treatment of Salivary Gland Tumors. He is also highly rated in 31 other conditions, according to our data. His top areas of expertise are Tongue Cancer, Throat Cancer, Laryngeal Cancer, and Salivary Gland Tumors. He is board certified in Otolaryngology and licensed to treat patients in Pennsylvania. Dr. Weinstein is currently accepting new patients.

What is the outlook (prognosis) for Salivary Gland Tumors?

Most salivary gland tumors are noncancerous and slow growing. Removing the tumor with surgery often cures the condition. In rare cases, the tumor is cancerous and further treatment is needed.

What are the possible complications of Salivary Gland Tumors?

Complications from the cancer or its treatment may include:

  • Spread of the cancer to other organs (metastasis).
  • In rare cases, injury during surgery to the nerve that controls movement of the face.
When should I contact a medical professional for Salivary Gland Tumors?

Contact your provider if you have any of the following:

  • Pain when eating or chewing
  • You notice a lump in the mouth, under the jaw, or in the neck that does not go away in 2 to 3 weeks or is getting larger
Head and neck glands
What are the latest Salivary Gland Tumors Clinical Trials?
A Single-centre, Double-blinded, Randomised, Placebo-controlled, Phase II Study to Investigate the Safety and Efficacy of Mesenchymal Stem Cell for Radiation-induced Hyposalivation and Xerostomia in Previous Head and Neck Cancer Patients (MESRIX-III)
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Quantification of 68-GaNOTA-Anti-HER2 VHH1 Uptake in Metastasis of Breast Carcinoma Patients and Assessment of Repeatability (VUBAR) - Pilot Study
What are the Latest Advances for Salivary Gland Tumors?
Metastatic Parotid Gland Carcinoma With ERBB2 Amplification With Complete Response to Fam-Trastuzumab Deruxtecan.
Diagnosis and treatment of secretory carcinoma arising from the oral minor salivary gland: Two case reports.
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Excessive toxicity of cabozantinib in a phase II study in patients with recurrent and/or metastatic salivary gland cancer.
Who are the sources who wrote this article ?

Published Date : December 08, 2021
Published By : Josef Shargorodsky, MD, MPH, Johns Hopkins University School of Medicine, Baltimore, MD. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Jackson NM, Mitchell JL, Walvekar RR. Inflammatory disorders of the salivary glands. In: Flint PW, Francis HW, Haughey BH, , et al, eds. Cummings Otolaryngology: Head and Neck Surgery. 7th ed. Philadelphia, PA: Elsevier; 2021:chap 83.

Markiewicz MR, Fernandes RP, Ord RA. Salivary gland disease. In: Fonseca RJ, ed. Oral and Maxillofacial Surgery. 3rd ed. St Louis, MO: Elsevier; 2018:chap 20.

National Cancer Institute website. Salivary gland cancer treatment (adult) (PDQ) - health professional version. www.cancer.gov/types/head-and-neck/hp/adult/salivary-gland-treatment-pdq. Updated December 20, 2021. Accessed February 16, 2022.

Wang JR, Bell DM, Hanna EY. Benign neoplasms of the salivary glands. In: Flint PW, Francis HW, Haughey BH, et al, eds. Cummings Otolaryngology: Head and Neck Surgery. 7th ed. Philadelphia, PA: Elsevier; 2021:chap 84.