Salivary Gland TumorsSymptoms, Doctors, Treatments, Advances & More
Learn About Salivary Gland Tumors
Salivary gland tumors are abnormal cells growing in the gland or in the tubes (ducts) that drain the salivary glands.
Tumor - salivary duct
Common conditions include: Acinic Cell Carcinoma of Salivary Glands
The salivary glands are located around the mouth. They produce saliva, which moistens food to help with chewing and swallowing. Saliva also helps to protect teeth from decay.
There are 3 main pairs of salivary glands. The parotid glands are the largest. They are located in each cheek in front of the ears. Two submandibular glands are under the floor of the mouth on both sides of the back of the jaw. Two sublingual glands are under the floor of the mouth next to the jaw on each side. There are also hundreds of small salivary glands lining the rest of the mouth. These are called the minor salivary glands.
Salivary glands empty saliva into the mouth through ducts that open at various places in the mouth.
Salivary gland tumors are rare. Swelling of the salivary glands is mostly due to:
- Cirrhosis of the liver
- Other cancers
- Salivary duct stones
- Salivary gland infections
- Dehydration
- Sarcoidosis
- Sjögren syndrome
The most common type of salivary gland tumor is a slow-growing noncancerous (benign) tumor of the parotid gland. The tumor gradually increases the size of the gland. Some of these tumors can be cancerous (malignant).
Symptoms may include any of the following:
- Firm, usually painless swelling in one of the salivary glands (in front of the ears, under the chin, or on the floor of the mouth). The swelling gradually increases.
- Difficulty moving one side of the face, known as facial nerve palsy.
Surgery is most often done to remove the affected salivary gland. If the tumor is benign, no other treatment is needed.
Radiation therapy or extensive surgery may be needed if the tumor is cancerous. Chemotherapy may be used when the disease has spread beyond the salivary glands.
Oral Dysplasia Program
Patrick Ha is an Otolaryngologist practicing medicine in San Francisco, California. Dr. Ha is rated as an Elite provider by MediFind in the treatment of Salivary Gland Tumors. He is also highly rated in 20 other conditions, according to our data. His clinical expertise encompasses Adenoid Cystic Carcinoma, Salivary Gland Tumors, Tongue Cancer, Gastrostomy, and Laryngectomy. Dr. Ha is board certified in American Board Of Otolaryngology, Otolaryngology. Dr. Ha is currently accepting new patients.
Johns Hopkins Outpatient Center
David Eisele is an Otolaryngologist practicing medicine in Baltimore, Maryland. He has been practicing medicine for over 44 years. Dr. Eisele is rated as an Elite provider by MediFind in the treatment of Salivary Gland Tumors. He is also highly rated in 15 other conditions, according to our data. His clinical expertise encompasses Salivary Duct Stones, Salivary Gland Tumors, Throat Cancer, Laryngectomy, and Gastrostomy. Dr. Eisele is board certified in Head And Neck Surgery. Dr. Eisele is currently accepting new patients.
UW Health|Carbone Cancer Center Head And Neck Cancer Clinic
Greg Hartig is an Otolaryngologist practicing medicine in Madison, Wisconsin. Dr. Hartig is rated as an Elite provider by MediFind in the treatment of Salivary Gland Tumors. He is also highly rated in 34 other conditions, according to our data. His clinical expertise encompasses Salivary Gland Tumors, Adenoid Cystic Carcinoma, Acinic Cell Carcinoma of Salivary Glands, Laryngectomy, and Thyroidectomy. Dr. Hartig is board certified in Otolaryngology - Head And Neck Surgery. Dr. Hartig is currently accepting new patients.
Most salivary gland tumors are noncancerous and slow growing. Removing the tumor with surgery often cures the condition. In rare cases, the tumor is cancerous and further treatment is needed.
Complications from the cancer or its treatment may include:
- Spread of the cancer to other organs (metastasis).
- In rare cases, injury during surgery to the nerve that controls movement of the face.
Contact your provider if you have any of the following:
- Pain when eating or chewing
- You notice a lump in the mouth, under the jaw, or in the neck that does not go away in 2 to 3 weeks or is getting larger
Summary: This study will evaluate the effectiveness of T-DXd in patients with HER2-positive (IHC 3+) locally advanced, unresectable, or metastatic solid tumors who have received prior systemic treatment for metastatic or advanced disease and have no satisfactory alternative treatment options in a real-world setting in the US
Summary: In France, squamous cell carcinomas of the head and neck (SCCHN) are the 5th most common cancer. 60% of patients present with locally advanced tumors (stage III/IV), characterized by a poor prognosis (5-year survival not exceeding 60%). The standard treatment consists of either surgical removal followed by adjuvant radiochemotherapy or exclusive radiochemotherapy. In case of locoregional recurrenc...
Published Date: October 21, 2025
Published By: Warren Brenner, MD, Oncologist, Lynn Cancer Institute, Boca Raton, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Alamoudi UA, Al Afif A. Benign neoplasms of the salivary glands. In: Francis HW, Haughey BH, Hillel AT, et al, eds. Cummings Otolaryngology: Head and Neck Surgery. 8th ed. Philadelphia, PA: Elsevier; 2026:chap 85.
Jackson NM, Mitchell JL, Walvekar RR. Inflammatory disorders of the salivary glands. In: Francis HW, Haughey BH, Hillel AT, et al, eds. Cummings Otolaryngology: Head and Neck Surgery. 8th ed. Philadelphia, PA: Elsevier; 2026:chap 84.
National Cancer Institute website. Salivary gland cancer treatment (PDQ) - health professional version. www.cancer.gov/types/head-and-neck/hp/adult/salivary-gland-treatment-pdq. Updated May 13, 2025. Accessed December 1, 2025.
Sirjani DB, Lewis JS, Beadle BM, Sunwoo JB, Finegersh A. Malignant neoplasms of the salivary glands. In: Francis HW, Haughey BH, Hillel AT, et al, eds. Cummings Otolaryngology: Head and Neck Surgery. 8th ed. Philadelphia, PA: Elsevier; 2026:chap 86.