SAPHO Syndrome Overview

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Learn About SAPHO Syndrome

What is the definition of SAPHO Syndrome?
SAPHO syndrome involves any combination of: Synovitis (inflammation of the joints), Acne, Pustulosis (thick yellow blisters containing pus) often on the palms and soles, Hyperostosis (increase in bone substance) and Osteitis (inflammation of the bones). The cause of SAPHO syndrome is unknown..
What are the alternative names for SAPHO Syndrome?
  • SAPHO syndrome
  • Acquired hyperostosis syndrome
  • Synovitis acne pustulosis hyperostosis osteitis
  • Synovitis, Acne, Pustlosis, Hyperostosis, and Osteomyelitis
Who are the top SAPHO Syndrome Local Doctors?
Daniel Wendling
Elite in SAPHO Syndrome
Daniel Wendling
Elite in SAPHO Syndrome
Daniel Wendling

CHU Gabriel Montpied

Clermont-ferrand, FR 

Daniel Wendling practices in Clermont-ferrand, France. Mr. Wendling is rated as an Elite expert by MediFind in the treatment of SAPHO Syndrome. His top areas of expertise are Arthritis, Ankylosing Spondylitis, Polymyalgia Rheumatica, Rhizomelic Pseudopolyarthritis, and Osteotomy.

Elite in SAPHO Syndrome
Yihan Cao
Elite in SAPHO Syndrome
Yihan Cao

Peking Union Medical College Hospital, Peking Union Medical College And Chinese Academy Of Medical Sciences

Beijing, CN 

Yihan Cao practices in Beijing, China. Cao is rated as an Elite expert by MediFind in the treatment of SAPHO Syndrome. Their top areas of expertise are SAPHO Syndrome, Synovitis, Acne, and Osteomyelitis in Children.

 
 
 
 
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Elite in SAPHO Syndrome
Hanna Bedzak-Przepiera
Elite in SAPHO Syndrome
Hanna Bedzak-Przepiera
Szczecin, ZP, PL 

Hanna Bedzak-Przepiera practices in Szczecin, Poland. Ms. Bedzak-Przepiera is rated as an Elite expert by MediFind in the treatment of SAPHO Syndrome. Her top areas of expertise are SAPHO Syndrome, Ankylosing Spondylitis, Psoriatic Arthritis, and Synovitis.

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What are the latest SAPHO Syndrome Clinical Trials?
Typological Study of Sleep Pathologies During Psoriatic Rheumatism and SAPHO Syndrome: Prospective Study Within the Paris Saint-Joseph Hospital Group
Typological Study of Sleep Pathologies During Psoriatic Rheumatism and SAPHO Syndrome: Prospective Study Within the Paris Saint-Joseph Hospital Group
Enrollment Status: Recruiting
Publish Date: July 25, 2025

Summary: Chronic inflammatory rheumatisms (CIR) are a source of motor disability and various comorbidities, particularly cardiovascular and metabolic. They also significantly impact patients' quality of life, including sleep disturbances. Among CIRs, psoriatic arthritis is a chronic inflammatory arthropathy associated with psoriasis, typically seronegative for rheumatoid factor. This heterogeneous disease ...

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A Multicenter, Randomized, Double-blind Clinical Trial Evaluating the Efficacy and Safety of Etanercept Versus Placebo in the Treatment of Patients With SAPHO Syndrome
A Multicenter, Randomized, Double-blind Clinical Trial Evaluating the Efficacy and Safety of Etanercept Versus Placebo in the Treatment of Patients With SAPHO Syndrome
Enrollment Status: Recruiting
Publish Date: November 19, 2024
Intervention Type: Drug
Study Phase: Phase 2/Phase 3

Summary: The study includes adult patients with SAPHO syndrome (ORPHA: 793), meeting the modified classification criteria according to Kahn (2003), with the ineffectiveness of standard treatment (patient's global assessment of the disease on the VAS scale greater than or equal to 4 cm with accompanying pain on the VAS scale greater than or equal to 4 cm) treated with non-steroidal anti-inflammatory drugs i...

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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center