Schizoaffective Disorder
Symptoms, Doctors, Treatments, Advances & More

Learn About Schizoaffective Disorder

What is the definition of Schizoaffective Disorder?

Schizoaffective disorder is a mental condition that causes both a loss of contact with reality (psychosis) and mood problems (depression or mania).

What are the alternative names for Schizoaffective Disorder?

Mood disorder - schizoaffective disorder; Psychosis - schizoaffective disorder

What are the causes of Schizoaffective Disorder?

The exact cause of schizoaffective disorder is unknown. Changes in genes and chemicals in the brain (neurotransmitters) may play a role.

Schizoaffective disorder is thought to be less common than schizophrenia and mood disorders. Women may have the condition more often than men. Schizoaffective disorder is rare in children.

What are the symptoms of Schizoaffective Disorder?

Symptoms of schizoaffective disorder are different in each person. Often, people with schizoaffective disorder seek treatment for problems with mood, daily function, or abnormal thoughts.

Psychosis and mood problems may occur at the same time or by themselves. The disorder may involve cycles of severe symptoms followed by improvement.

The symptoms of schizoaffective disorder can include:

  • Changes in appetite and energy
  • Disorganized speech that is not logical
  • False beliefs (delusions), such as thinking someone is trying to harm you (paranoia) or thinking that special messages are hidden in common places (delusions of reference)
  • Lack of concern with hygiene or grooming
  • Mood that is either too good, or depressed or irritable
  • Problems sleeping
  • Problems with concentration
  • Sadness or hopelessness
  • Seeing or hearing things that are not there (hallucinations)
  • Social isolation
  • Speaking so quickly that others cannot interrupt you
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What are the current treatments for Schizoaffective Disorder?

Treatment can vary. In general, your provider will prescribe medicines to improve your mood and treat psychosis:

  • Antipsychotic medicines are used to treat psychotic symptoms.
  • Antidepressant medicines, or mood stabilizers, may be prescribed to improve mood.

Talk therapy can help with creating plans, solving problems, and maintaining relationships. Group therapy can help with social isolation.

Support and work training may be helpful for work skills, relationships, money management, and living situations.

Who are the top Schizoaffective Disorder Local Doctors?
Elite in Schizoaffective Disorder
Psychiatry | Psychology
Elite in Schizoaffective Disorder
Psychiatry | Psychology

Baylor College Of Medicine - Psychiatry

1977 Butler Blvd, Ste E4.400, BCM350-2, 
Houston, TX 
Languages Spoken:
English
Accepting New Patients
Offers Telehealth

Olaoluwa Okusaga, MD, is dedicated to delivering high-quality, compassionate care to Houston and nearby communities. Olaoluwa Okusaga specializes in Psychiatry and works at BCM Psychiatry. To make an appointment, please call (713) 798-4857. To review all accepted insurance carriers, please visit: https://www.stlukeshealth.org/patients-visitors/patients/billing-insurance/insurances-accepted. Dr. Okusaga is rated as an Elite provider by MediFind in the treatment of Schizoaffective Disorder. His top areas of expertise are Schizoaffective Disorder, Schizophrenia, Seasonal Affective Disorder (SAD), and Bipolar Disorder (BPD).

Leonard A. Lado
Advanced in Schizoaffective Disorder
Psychiatry | Neurology
Advanced in Schizoaffective Disorder
Psychiatry | Neurology

Lado Healing Institute

9410 Fountain Medical Court, Ste# 200, 
Bonita Springs, FL 
Languages Spoken:
English, Hungarian, Spanish
Accepting New Patients
Offers Telehealth

Leonard Lado is a Neurologist and a Psychiatrist in Bonita Springs, Florida. Dr. Lado is rated as an Advanced provider by MediFind in the treatment of Schizoaffective Disorder. His top areas of expertise are Bipolar Disorder (BPD), Seasonal Affective Disorder (SAD), Major Depression, and Generalized Anxiety Disorder (GAD). Dr. Lado is currently accepting new patients.

 
 
 
 
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Zhabiz Kazeminezhad
Advanced in Schizoaffective Disorder
Advanced in Schizoaffective Disorder

Tower Health Medical Group Psychiatry - Collegeville

305 Second Ave, 
Collegeville, PA 
Languages Spoken:
English

. Dr. Kazeminezhad is rated as an Advanced provider by MediFind in the treatment of Schizoaffective Disorder. Her top areas of expertise are Schizophrenia, Schizoaffective Disorder, Bipolar Disorder (BPD), and Major Depression.

What is the outlook (prognosis) for Schizoaffective Disorder?

People with schizoaffective disorder have a greater chance of going back to their previous level of function than do people with most other psychotic disorders. But long-term treatment is often needed, and results vary from person to person.

What are the possible complications of Schizoaffective Disorder?

Complications are similar to those for schizophrenia and major mood disorders. These include:

  • Substance misuse
  • Problems following medical treatment and therapy
  • Problems due to manic behavior (for example, spending sprees, overly sexual behavior)
  • Suicidal behavior
When should I contact a medical professional for Schizoaffective Disorder?

Contact your provider if you or someone you know is experiencing any of the following:

  • Depression with feelings of hopelessness or helplessness
  • Inability to care for basic personal needs
  • Increase in energy and involvement in risky behavior that is sudden and not normal for you (for instance, going days without sleeping and feeling no need for sleep)
  • Strange or unusual thoughts or perceptions
  • Symptoms that get worse or do not improve with treatment
  • Thoughts of suicide or of harming others

If you or someone you know is thinking about suicide, call or text 988 or chat 988lifeline.org. You can also call 1-800-273-8255 (1-800-273-TALK). The 988 Suicide and Crisis Lifeline provides free and confidential support 24/7, anytime day or night.

You can also call 911 or the local emergency number or go to the hospital emergency room. DO NOT delay.

If someone you know has attempted suicide, call 911 or the local emergency number right away. DO NOT leave the person alone, even after you have called for help.

What are the latest Schizoaffective Disorder Clinical Trials?
A Phase 1b, Open-label Study to Determine the Pharmacokinetics, Safety, and Tolerability of Single, Ascending Doses of Lumateperone Long-acting Injectable Formulations Administered Intramuscularly to Patients With Schizophrenia or Schizoaffective Disorder

Summary: Study ITI-007-037 is a Phase 1b, open-label study to evaluate the safety, tolerability, and PK of lumateperone long-acting injectable (LAI) formulations after a single intramuscular injection in patients with stale schizophrenia or schizoaffective disorder.

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Who are the sources who wrote this article ?

Published Date: May 04, 2024
Published By: Fred K. Berger, MD, addiction and forensic psychiatrist, Scripps Memorial Hospital, La Jolla, CA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

American Psychiatric Association website. Schizophrenia spectrum and other psychotic disorders. Diagnostic and Statistical Manual of Mental Disorders. 5th ed. Text Revision (DSM-5-TR), Washington, DC: American Psychiatric Association Publishing; 2022.

Lim C, Paudel S, Holt D, Freudenreich O. Psychosis and schizophrenia. In: Stern TA, Wilens TE, Fava M, eds. Massachusetts General Hospital Comprehensive Clinical Psychiatry. 3rd ed. Philadelphia, PA: Elsevier; 2025:chap 27.

Lyness JM, Lee HB. Psychiatric disorders in medical practice. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 362.