SchizophreniaSymptoms, Doctors, Treatments, Advances & More
Learn About Schizophrenia
Schizophrenia is a mental disorder that makes it hard to tell the difference between what is real and not real.
It also makes it hard to think clearly, have normal emotional responses, and act normally in social situations.
Psychosis - schizophrenia; Psychotic disorders - schizophrenia
Schizophrenia is a complex illness. Mental health experts are not sure what causes it. Genes may play a role.
Schizophrenia occurs more often in men than women. It usually begins in the late teen years or young adult years, but it may also begin later in life. In women, it tends to begin slightly later.
Schizophrenia in children younger than 13 is rare and can be hard to tell apart from other developmental problems.
Symptoms usually develop slowly over months or years. The person may have many symptoms, or only a few.
People with schizophrenia may have trouble keeping friends and jobs. They may also have problems with anxiety, depression, and suicidal thoughts or behaviors.
Early symptoms may include:
- Irritable or tense feelings
- Trouble concentrating
- Trouble sleeping
As the illness continues, the person may have problems with thinking, emotions, and behavior, including:
- Hearing or seeing things that are not there (hallucinations)
- Isolation
- Reduced emotions in tone of voice or expression of face
- Problems with understanding and making decisions
- Problems paying attention and following through with activities
- Strongly held beliefs that are not real (delusions)
- Talking in a way that does not make sense
During an episode of schizophrenia, the person may need to stay in the hospital for safety reasons.
MEDICINES
Antipsychotic medicines (antipsychotics) are the most effective treatment for schizophrenia. They change the balance of chemicals in the brain and can help regulate symptoms.
These medicines can cause side effects, but many side effects can be managed. Side effects should not prevent the person from getting treated for this serious condition.
Common side effects from antipsychotics may include:
- Dizziness
- Feelings of restlessness or jitteriness
- Sleepiness (sedation)
- Slowed movements
- Tremors
- Weight gain
- Diabetes
- High cholesterol
Long-term use of antipsychotics may increase the risk for a movement disorder called tardive dyskinesia. This condition causes repeated movements that the person cannot control. Contact your health care provider right away if you think you or your family member may have this condition due to a medicine.
When schizophrenia does not improve with antipsychotic medicines, other medicines may be tried.
Schizophrenia is a life-long illness. Most people with this condition need to stay on antipsychotic medicines for life.
SUPPORT PROGRAMS AND THERAPIES
Support therapy may be helpful for many people with schizophrenia. Behavioral techniques, such as social skills training, can help the person function better in social and work situations. Job training and relationship-building classes are also important.
Many resources for help are available in the community. The following may help find them:
- National Institute of Mental Health (NIMH) -- nimh.nih.gov/health/find-help
- National Alliance on Mental Illness (NAMI) -- www.nami.org/
- Centers for Disease Control and Prevention (CDC) -- www.cdc.gov/mental-health/caring/index.html
Family members and caregivers are very important during treatment. Therapy can teach important skills, such as:
- Coping with symptoms that continue, even while taking medicines
- Following a healthy lifestyle, including getting enough sleep and staying away from recreational drugs
- Taking medicines correctly and managing side effects
- Watching for the return of symptoms and knowing what to do when they return
- Getting the right support services
APILAX Medical PLLC
Andrei Pikalov is a Psychiatrist practicing medicine in Palm Coast, Florida. Dr. Pikalov is rated as an Elite provider by MediFind in the treatment of Schizophrenia. He is also highly rated in 3 other conditions, according to our data. His clinical expertise encompasses Bipolar Disorder (BPD), Schizophrenia, and Major Depression. Dr. Pikalov is board certified in ABPN: Americal Board Of Psychiatry And Neurology.
Beth Israel Deaconess Medical Center
Matcheri Keshavan is a Psychiatrist practicing medicine in Boston, Massachusetts. Dr. Keshavan is rated as an Elite provider by MediFind in the treatment of Schizophrenia. He is also highly rated in 4 other conditions, according to our data. His clinical expertise encompasses Schizophrenia, Bipolar Disorder (BPD), Schizoaffective Disorder, and Autism Spectrum Disorder. Dr. Keshavan is board certified in American Board Of Psychiatry And Neurology.
Peter Falkai practices practicing medicine in Goettingen, Germany. Mr. Falkai is rated as an Elite expert by MediFind in the treatment of Schizophrenia. He is also highly rated in 7 other conditions, according to our data. His clinical expertise encompasses Schizophrenia, Bipolar Disorder (BPD), Schizoaffective Disorder, and Major Depression.
The outlook is hard to predict. Most of the time, symptoms improve with medicines. But many people may have trouble functioning. They are at risk for repeated episodes, especially during the early stages of the illness. People with schizophrenia are also at increased risk for suicide.
People with schizophrenia may need housing, job training, and other community support programs. Those with the most severe forms of this disorder may not be able to live alone. They may need to live in group homes or other long-term, structured residences.
Symptoms are very likely to return when antipsychotic medicine is stopped.
Having schizophrenia increases the risk for:
- Developing a problem with alcohol or illegal drugs. Using these substances increases the chances that symptoms will return.
- Physical illness. This is due to an inactive lifestyle and side effects of medicines.
- Suicide.
Contact your provider if you (or a family member):
- Hear voices telling you to hurt yourself or others
- Have the urge to hurt yourself or others
- Feel scared or overwhelmed
- See or hear things that are not there
- Feel that you cannot leave the house
- Feel that you are not able to care for yourself
If you are thinking about hurting yourself or others, call or text 988 or chat 988lifeline.org. You can also call 1-800-273-8255 (1-800-273-TALK). The 988 Suicide and Crisis Lifeline provides free and confidential support 24/7, anytime day or night.
You can also call 911 or the local emergency number or go to the hospital emergency room. DO NOT delay.
If someone you know has attempted suicide, call 911 or the local emergency number right away. DO NOT leave the person alone, even after you have called for help.
Schizophrenia cannot be prevented.
Symptoms may be prevented by taking medicine exactly as your provider instructed. Symptoms are likely to return if medicine is stopped.
Changing or stopping medicines should only be done by the provider who prescribed them.
Summary: The aim of the present study is to detect changes in the dopamine system in the brain of patients with schizophrenia, especially when pretreated with antipsychotic medication. Here, the investigators want to find out whether the treatment with these drugs can cause permanent changes in docking points (receptors) of dopamine in the brain. It will be examined whether number and response of dopamine ...
Summary: The purpose of this study is to evaluate the efficacy and safety of KarXT for treatment of Schizophrenia in adolescents.
Published Date: July 11, 2026
Published By: Fred K. Berger, MD, DLFAPA, board-certified in psychiatry, Scripps Memorial Hospital, La Jolla, CA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
American Psychiatric Association. Schizophrenia spectrum and other psychotic disorders. Diagnostic and Statistical Manual of Mental Disorders. 5th ed. Text Revision (DSM-5-TR), Washington, DC: American Psychiatric Association Publishing; 2022.
Jauhar S, Johnstone M, McKenna PJ. Schizophrenia. Lancet. 2022;399(10323):473-486. PMID: 35093231 pubmed.ncbi.nlm.nih.gov/35093231/.
Lim C, Paudel S, Holt DJ, Freudenreich O. Psychosis and schizophrenia. In: Stern TA, Wilens TE, Fava M, eds. Massachusetts General Hospital Comprehensive Clinical Psychiatry. 3rd ed. Philadelphia, PA: Elsevier; 2025:chap 27.
Substance Abuse and Mental Health Services Administration website. Schizophrenia. www.samhsa.gov/mental-health/what-is-mental-health/conditions/schizophrenia. Updated December 23, 2025. Accessed August 25, 2026.