Comparative Effectiveness of Cognitive Enhancement Therapy vs. Social Skills Training in Serious Mental Illness
Status: Recruiting
Location: See all (5) locations...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
To compare two evidence-based treatments, Cognitive Enhancement Therapy (CET) and Social Skills Training (SST) that have been shown in meta-analyses and in our own research to be effective to improve community functioning. The investigators will test the impact of CET and SST on community functioning, with special attention to their relative effectiveness for patients differing in baseline cognitive skills and age. The research uses a cluster design in which different mental health service centers are randomized to one of the two treatments.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:
• age 18 to 65;
• DSM-5 diagnosis of schizophrenia or schizoaffective or schizophreniform disorder (confirmed via the MINI diagnostic interview);
• estimated IQ of \> 70 (established via WTAR).
Locations
United States
Connecticut
Hartford Hospital - Institute of Living
RECRUITING
Hartford
Massachusetts
Beth Israel Deaconess Medical Center
ACTIVE_NOT_RECRUITING
Boston
Massachusetts Mental Health Center
RECRUITING
Boston
UMass Medical School
RECRUITING
Worcester
Maine
Maine Medical Center
RECRUITING
Portland
Contact Information
Primary
Jennifer Sabbagh
jsabbagh@bidmc.harvard.edu
617-975-8545
Backup
Blanche Spindell
bspindel@bidmc.harvard.edu
617-735-4261
Time Frame
Start Date: 2021-06-01
Estimated Completion Date: 2026-01-31
Participants
Target number of participants: 378
Treatments
Experimental: Cognitive Enhancement Therapy
CET is a comprehensive manualized cognitive remediation program designed to maximize gains in social functioning by integrating computer-based training to enhance neurocognition with group-based exercises to improve social cognition.
Active_comparator: Social Skills Training
The HOPES social rehabilitation program uses the principles of SST (modeling, role playing, positive and corrective feedback, homework assignments, in vivo skills practice), designed to improve both psychosocial functioning and preventive health..
Related Therapeutic Areas
Sponsors
Leads: Beth Israel Deaconess Medical Center
Collaborators: Patient-Centered Outcomes Research Institute