Repetitive Transcranial Magnetic Stimulation in Subjects With Early Psychosis and The Functional Connectivity Biotypes
The present study plans to explore different cortical targets of repetitive transcranial magnetic stimulation (rTMS) for populations at the early phase of psychosis, including those at clinical high risk of psychosis and in the first episode of psychosis. The clinical augmentation efficacy will be associated with the brain functional connectivity of these populations.
• Meeting the syndrome of clinical high risk of psychosis, identified by a face-to-face interview using the Chinese version of Structured Interview for Prodromal Syndromes / Scale of Prodromal Symptoms (SIPS/SOPS);
• Given the written consent for participation.
• Age between 14-45 years old;
• IQ\>69;
• PANSS total scores \>= 55 or BVMT-R score \<= 26;
• Meeting the DSM-V diagnostic criteria for schizophrenia spectrum disorders;
• Given the written consent for participation.
• Age between 14-45 years old;
• IQ\>69;
• during the first episode without a full remission;
• PANSS total scores \>= 55 or BVMT-R score \<= 26;
• within receiving rTMS, patients can receive second-generation antipsychotics except clozapine with stable dosages