The Neuro-VR Study: A Pilot Study Investigating an Innovative Virtual Reality-based Intervention Employing Neurofeedback to Increase Tolerability and Therapy Efficacy in Psychosis
The primary goal of this pilot study is to examine the feasibility and acceptability of augmenting a Virtual Reality-based intervention for treating auditory hallucinations in schizophrenia with electroencephalogram (EEG)-based neurofeedback. The main questions it aims to answer are: 1. Is Virtual Reality -based therapy supplemented with EEG-based neurofeedback (VR-NF) a feasible and acceptable treatment for auditory hallucinations? 2. Will VR-NF show indications of being more effective than Virtual Reality-based therapy alone in reducing the severity of auditory hallucinations, improving daily functioning, and enhancing quality of life? Researchers will compare VR-NF to Virtual Reality-based therapy alone to evaluate therapy effectiveness. Participants will be allocated to receive 8 sessions of either VR-NF or Virtual Reality-based therapy alone. All participants will undergo a thorough assessment at baseline, and at 12 weeks post-baseline.
• Ability to give informed consent
• Age of 18-65 years
• Diagnosis of schizophrenia spectrum disorder (ICD-10 codes: F20, F22-23; F25-29)
• Symtoms of Auditory Verbal Hallucinations within at least the past 3 months (corresponding to SAPS score of 3 or more)
• Identification of at least one dominant voice
• No changes in antipsychotic medications four weeks prior to inclusion in the project
• No planned changes in antipsychotic medication in the 12 weeks following inclusion in the project
• A command of Danish or English sufficient to engage in therapy