Social Cognition Training in Individuals With Huntington's Disease: A Feasibility Study

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Individuals with Huntington's Disease have impaired social cognition, which is the domain of cognition that allows individuals to understand others' perspectives so that they can navigate interpersonal actions successfully (e.g., understanding someone may be sad based of their facial emotion or tone of voice and then responding in a sympathetic manner). Impaired social cognition is associated with impaired social functioning, poor psychological wellbeing and increased caregiver burden, which is known to be significant among those who care for individuals with Huntington's Disease. Computerized social cognition training has been shown to improve social cognition in individuals with schizophrenia, who, like individuals with Huntington's disease, have cognitive impairments. The investigators propose a pilot study of computerized social cognition training in individuals with Huntington's disease. This will be a feasibility study that aims to show that social cognition training in HD can be studied in preparation for a larger randomized controlled trial. The investigators hypothesize that social cognition training can improve social cognition, social functioning, and quality of life in individuals with Huntington's Disease and decrease caregiver burden among those who care for individuals with Huntington's Disease.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:

• Diagnosed with Huntington's Disease based on genetic testing

• Must be between 18 and 65 years of age

• Native English speaker who is literate in English

• Stable psychotropic medication regimen for 4 weeks

• Must have a score of somewhat easily on all items in the CPQ-12

• MOCA \>18

• Completed 12 years of schooling

• Access to laptop or mobile device

• Willingness to come in person 6-12 weeks after first visit

• Lives with patient

• Must be between 18 and 65 years of age

• Native English speaker who is literate in English

• MOCA \>26

• Willingness to come in person within 6-12 weeks after first visit

Locations
United States
Illinois
Rush University Medical Center
RECRUITING
Chicago
Contact Information
Primary
Tyler Svymbersky
Tyler_Svymbersky@rush.edu
312-563-0676
Time Frame
Start Date: 2025-11-15
Estimated Completion Date: 2028-07-15
Participants
Target number of participants: 20
Treatments
Experimental: Social Cognition Training Group
Sponsors
Leads: Rush University Medical Center

This content was sourced from clinicaltrials.gov