The Effects of Adjunctive Transcranial Direct Current Stimulation on Treatment Adherence in Schizophrenia
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study seeks to explore the effects of transcranial direct current stimulation (tDCS), a non-invasive method of brain stimulation, as an adjunctive treatment to improve antipsychotic medication adherence in patients with schizophrenia (SCZ). The investigators hypothesize that 20 sessions of tDCS will improve medication nonadherence in patients with SCZ.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Male or female participants of any race or ethnicity
• Inpatients or outpatients ≥18 years of age
• DSM-V diagnosis of SCZ or schizoaffective disorder
• Capable of consenting to participate in the research study
• On a stable dose of antipsychotic drug and other concomitant medications for at least 2 months, and unlikely to undergo changes in dose during the study
Locations
Other Locations
Canada
Centre for Addiction and Mental Health
RECRUITING
Toronto
Contact Information
Primary
Philip Gerretsen, MD, PhD
philip.gerretsen@camh.ca
416-535-8501
Backup
Ariel Graff, MD, PhD
ariel.graff@camh.ca
416-535-8501
Time Frame
Start Date: 2019-08-15
Estimated Completion Date: 2026-03-31
Participants
Target number of participants: 106
Treatments
Experimental: Active TDCS
In the active condition, a constant current of 2 mA intensity will be applied for 20 min to the parietal regions, using P3 as the cathode and P4 as the anode.
Sham_comparator: Sham TDCS
In the sham condition, stimulation will be administered using the same parameters at the site of active treatment, but the current will be turned off after 30 seconds.
Related Therapeutic Areas
Sponsors
Leads: Centre for Addiction and Mental Health