Predicting Psychotic Relapse Using Speech-Based Early Detection

Status: Recruiting
Location: See all (3) locations...
Study Type: Observational
SUMMARY

Psychotic disorders, including schizophrenia and affective psychosis, are severe mental health conditions marked by recurrent episodes that contribute to long-term disability. Relapses, characterized by the re-emergence of psychotic symptoms after remission, are a critical factor in the progression of these disorders, increasing risks such as suicide, cognitive impairment, and unemployment. This study aims to develop a novel, speech-based digital model to predict relapses in individuals with psychosis. Building on previous research into language abnormalities in schizophrenia, the study will employ a longitudinal design across Early Psychosis Intervention (EPI) clinics in Ontario and Quebec to advance relapse prediction

Eligibility
Participation Requirements
Sex: All
Minimum Age: 16
Healthy Volunteers: f
View:

• Age must be 16 years and older

• Diagnosis must meet DSM-5 criteria for psychotic disorders, including schizophrenia, schizoaffective disorder, or related conditions

• Fluency in English or French

• Must be currently receiving treatment through an EPI program

Locations
Other Locations
Canada
Robarts Research Institute
RECRUITING
London
Douglas Mental Health University Institute
RECRUITING
Montreal
Vitam
RECRUITING
Québec
Contact Information
Primary
Lena Palaniyappan, MD, PHD
lena.palaniyappan@mcgill.ca
5147616131
Time Frame
Start Date: 2024-05-27
Estimated Completion Date: 2029-07-01
Participants
Target number of participants: 250
Treatments
Early Psychosis Patients
This study will participants recruited from three Early Psychosis Intervention (EPI) programs across Ontario and Quebec.~This group will consist of approximately 250 patients experiencing or having experienced psychosis, enrolled in the EPI programs.
Related Therapeutic Areas
Sponsors
Leads: Douglas Mental Health University Institute

This content was sourced from clinicaltrials.gov