Schizophrenia Clinical Trials

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Pilot Study of the Cognitive and Neurobiological Effects of the Clubhouse Model of Psychosocial Rehabilitation for Schizophrenia and Related Conditions

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The purpose of this study is to understand how different types of community-based mental health care affect thinking abilities, daily functioning, and brain activity in adults with schizophrenia and related conditions. The investigators are especially interested in learning whether the Clubhouse Model-a structured, supportive community for individuals with mental illness-has unique benefits compared to standard outpatient mental health services. If participants decide to join, they will be asked to complete a total of six study visits with the research team over the course of your participation. Three of these study visits are at the beginning (baseline) and the remaining three are six months later. Two of the three visits will includes interviews, questionnaires, and thinking and memory tasks (cognitive testing) and one session will be an MRI brain scan, which is a safe and non-invasive imaging procedure. The total time required for each visit will be approximately 90 minutes to two hours. Participants may take breaks as needed.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 50
Healthy Volunteers: f
View:

• (1) have a DSM-V diagnosis of schizophrenia, schizoaffective disorder, or schizophreniform confirmed by diagnostic assessment and medical record review

• (2) between the ages of 18-50

• (3) stabilized on psychotropic medication as indicated by no changes to the primary psychiatric medication in the last month

• (4) able to read and speak fluent English at a sixth grade level or higher for purposes of informed consent and cognitive testing

• For Clubhouse members, they must be a first-time, newly enrolled member

Locations
United States
Ohio
Case Western Reserve University
RECRUITING
Cleveland
Contact Information
Primary
Jessica A Wojtalik, PhD
reach-study@case.edu
216-368-1329
Time Frame
Start Date: 2026-08-30
Estimated Completion Date: 2028-01-30
Participants
Target number of participants: 30
Treatments
Experimental: Clubhouse Model of Psychosocial Rehabilitation for Serious Mental Illness
The Clubhouse Model (CM) is a strengths-focused, evidence-based, and comprehensive approach to psychosocial rehabilitation for serious mental illness. The CM uses an intentional community of support to create a safe and holistic setting to practice real-world functioning. The core of the CM is the 'work-ordered day,' a concept where members, as opposed to patients, are integral to and needed for the successful daily operation of the Clubhouse. Members choose a 'work unit' each day of attendance. Most clubhouses have four work units, such as (1) Administration (e.g., database management); (2) Hospitality (e.g., Clubhouse cafe); (3) Membership (e.g., employment programs); and (4) Communications (e.g., newsletter). Other unique aspects include its voluntary and humanistic nature, prioritization of member choice, unrestricted and flexible membership, and the elimination of provider-patient hierarchy. The CM has a sophisticated accreditation process based on 37 international standards.
Active_comparator: Usual Community-Based Mental Health Care
Usual care includes services typically available in the community at mental health agencies, including case management, Assertive Community Treatment, counseling, peer support services, psychoeducational support groups, family support groups, supported education/employment, permanent supportive housing, and medication management.
Related Therapeutic Areas
Sponsors
Collaborators: Magnolia Clubhouse, The Centers
Leads: Case Western Reserve University

This content was sourced from clinicaltrials.gov