Towards a Personalized Medicine Approach to Psychological Treatment for Psychosis
This study aims to compare the efficacy of classical Metacognitive Training (MCT) and personalized Metacognitive Training (P-MCT) for individuals with psychosis. MCT is a psychoeducational program derived from cognitive-behavioral therapy (CBT) that targets cognitive biases associated with psychotic symptoms. The goal is to assess which intervention is more effective to improve the overall functioning of individuals with psychosis. The study will use machine learning to personalize the treatment approach and evaluate its impact on clinical symptoms, cognitive functions, and quality of life.
• Adults, 18 - 65 years of age.
• Patient affiliated to health insurance
• Inpatients and outpatients with DSM-5 diagnosis of schizophrenia spectrum disorder.
• Presence of positive symptoms at inclusion (PANSS delusions, suspiciousness or grandiosity ≥3).
• Stable condition with no expected changes in medication or symptoms during the last 3 months (information from clinical services, note that stable condition includes lack of suicidality).
• Patient providing informed consent.