Schizophrenia Clinical Trials

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TMS for Negative Symptoms in Schizophrenia Spectrum Disorders

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The purpose of this study is to determine if repetitive transcranial magnetic stimulation (rTMS) applied to angular gyrus (AG) will improve negative symptoms and/or other psychosis symptoms in schizophrenia spectrum disorders (SSD) patients compared with prefrontal cortex (PFC) or sham.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 60
Healthy Volunteers: f
View:

• Ability to give written informed consent

• Diagnosed with schizophrenia-spectrum disorder and Evaluation to Sign Consent (ESC) above 10.

• Is currently under the care of a licensed primary care provider or mental healthcare provider (e.g., psychiatrist, psychologist, nurse practitioner, licensed clinical social worker).

• Have negative symptoms as determined by BNSS score of 20 or more.

• Agrees to provide written permission, as requested, to allow any and all forms of communication between the investigators and study staff and any health care provider who currently provides and/or has provided service to the subject within two years of study enrollment

Locations
United States
Texas
The University of Texas Health Science Center at Houston
RECRUITING
Houston
Contact Information
Primary
Xiaoming Du, PhD
Xiaoming.Du@uth.tmc.edu
443-882-9717
Backup
Keiko Kunitoki
Keiko.Kunitoki@uth.tmc.edu
(713) 486-2700
Time Frame
Start Date: 2026-03-13
Estimated Completion Date: 2030-11-30
Participants
Target number of participants: 20
Treatments
Experimental: AG TMS
Sham_comparator: PFC sham
Sham_comparator: AG Sham
Active_comparator: PFC TMS
Related Therapeutic Areas
Sponsors
Leads: The University of Texas Health Science Center, Houston

This content was sourced from clinicaltrials.gov