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An Open-Label Study to Assess the Long-Term Safety, Tolerability, and Effectiveness of ML-007C-MA in Adult Participants With Schizophrenia

Status: Recruiting
Location: See all (5) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 2
SUMMARY

ML-007C-MA-212 is a 52-week open-label study designed to evaluate the long-term safety, tolerability, and effectiveness of ML-007C-MA in participants with schizophrenia who have recently completed an antecedent study (ML-007C-MA-211) or enroll directly (De Novo Cohort).

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:

• Must be able and willing to provide informed consent for all required study procedures.

• Has a primary diagnosis of schizophrenia based on the DSM-5 criteria that is confirmed by semi-structured clinical interview (Mini International Neuropsychiatric Interview for DSM-5).

• May benefit from long-term pharmacotherapy for schizophrenia, based on assessment of the investigator.

• Is appropriate for an outpatient level of care and resides in a stable living situation, based on assessment of the investigator.

• Has an identified reliable informant(s) available to participate in relevant assessments. Site staff may serve as the informant if the site has had regular contact with the participant for \>1 year.

Locations
United States
California
Clinical Site
RECRUITING
Lemon Grove
Florida
Clinical Site
RECRUITING
Miami Lakes
Illinois
Clinical Site
RECRUITING
Chicago
New York
Clinical Site
RECRUITING
Staten Island
Texas
Clinical Site
RECRUITING
Desoto
Contact Information
Primary
Clinical Trials Contact Center
ML-007C-MA-SCZ@maplightrx.com
+1 650 839 4385
Time Frame
Start Date: 2026-03-31
Estimated Completion Date: 2030-02
Participants
Target number of participants: 500
Treatments
Experimental: ML-007C-MA
Related Therapeutic Areas
Sponsors
Leads: MapLight Therapeutics

This content was sourced from clinicaltrials.gov

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