Schizophrenia Clinical Trials

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The Effect of a 2-month Somatic Serious Games on the Cognition of Schizophrenia Patients

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Schizophrenia is a common and severe mental disorder that imposes a significant burden on patients. Cognitive impairment can be regarded as one of the core symptoms of schizophrenia, which is prevalent among patients with schizophrenia. In recent years, digital rehabilitation therapy based on games has shown a remarkable development trend among schizophrenia patients. Serious games, or application games, refer to those games aimed not only for entertainment. They can educate, train, or change the behavior of players through interesting intervention forms and have been applied in many healthcare fields. This study aims to develop a somatosensory interactive game for patients with cognitive impairment of schizophrenia to improve their cognitive functions and verify its effectiveness and feasibility through a randomized controlled trial.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 45
Healthy Volunteers: f
View:

• Registered in the Shanghai Mental Health Information Management System and hospitalized in the designated district-level mental health center wards;

• Schizophrenia patients meeting the diagnostic criteria of schizophrenia in the International Classification of Diseases (ICD-10);

• 18 - 45 years old;

• Good self-care ability;

• Clinically stable (without acute exacerbation) for at least 1 week before enrollment, with a stable dose of antipsychotic drugs or other concomitant psychotropic drugs for at least 1 week;

• No hand disabilities, and can use mobile phones or tablets normally;

• Have a primary school education or above;

• Normal vision and hearing, or within the normal range after correction;

• Own and be able to independently use a smart phone or other electronic devices;

⁃ Patients and their families have given informed consent to this study, and voluntarily cooperate to participate in the intervention and sign the informed consent form.

Locations
Other Locations
China
Shanghai Mental Health Center
RECRUITING
Shanghai
Contact Information
Primary
Weibo Zhang
zhangweibo600@163.com
86-13764694223
Time Frame
Start Date: 2026-04-19
Estimated Completion Date: 2028-07
Participants
Target number of participants: 84
Treatments
Experimental: Intervention group (Gamified Digital Rehabilitation)
The group member (n = 42) will receive approximately 30 minutes of digital rehabilitation training at least three times a week for 8 weeks, with professional supervision and guidance as they use the games. Cognitive function and quality of life were assessed at baseline and follow-up.
No_intervention: Controlled group (Routine Rehabilitation Group)
Participants in this arm (n = 42) will receive routine inpatient psychiatric rehabilitation and care during the same period.
Related Therapeutic Areas
Sponsors
Leads: Shanghai Mental Health Center

This content was sourced from clinicaltrials.gov