Neuronal Effects of Exercise in Schizophrenia

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study plans to learn more about how common drugs prescribed to individuals with schizophrenia contribute to weight gain, as well as how exercise and diet impact appetite and the brain's response to food. In this study, the investigators will be evaluating how participants' brains respond to food images as well as asking questions about their food preferences and intake and clinical symptoms. The investigators may also ask participants to complete an exercise or diet intervention to see how this changes brain responses or food preferences.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 21
Maximum Age: 70
Healthy Volunteers: f
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• Diagnosis of schizophrenia or schizoaffective disorder

• Between 21 and 70 years of age

• Currently prescribed either olanzapine, risperidone, clozapine, or haloperidol, OR not currently being treated with any neuroleptic medications

• Weight stable within 5 percent for the last 6 months

Locations
United States
Colorado
University of Colorado Anschutz Medical Campus
RECRUITING
Aurora
Contact Information
Primary
Kristina T Legget, Ph.D.
kristina.legget@ucdenver.edu
303-724-5809
Time Frame
Start Date: 2014-08
Estimated Completion Date: 2025-09
Participants
Target number of participants: 140
Treatments
Experimental: Exercise intervention
10 weeks of a moderate exercise intervention
Active_comparator: Diet intervention
10 weeks of a diet intervention
Related Therapeutic Areas
Sponsors
Collaborators: National Institute of Mental Health (NIMH), National Center for Advancing Translational Sciences (NCATS)
Leads: University of Colorado, Denver

This content was sourced from clinicaltrials.gov