Radiosurgery Induced Ototoxicity in Patients Treated for a Vestibular Schwannoma

Status: Recruiting
Location: See location...
Intervention Type: Radiation
Study Type: Observational
SUMMARY

The investigators aim to study the impact of stereotactic radiosurgery, for the treatment of vestibular Schwannoma, on the cochlear, vestibular, gustatory, and facial nerve functions and compare it with a conservatively treated group. The predictive value of radiological tumor characteristics on hearing preservation and vestibular function will be also evaluated. Additionally, the investigators will invite patients with vestibular Schwannoma to fill out questionnaires to assess their quality of life.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Aged 18 years or above

• Patients with unilateral VS treated either with SRS or MRI-based observation strategy, as proposed by the institution's skull base tumor board independently of the study

• Patients willing to take part in the study and give their informed consent

Locations
Other Locations
Switzerland
Service d'ORL et Chirurge cervico-faciale, Hopitaux Universitaires de Genève
RECRUITING
Geneva
Contact Information
Primary
Pascal Senn
pascal.senn@hcuge.ch
0223728244
Time Frame
Start Date: 2023-01-24
Estimated Completion Date: 2030-11-15
Participants
Target number of participants: 258
Treatments
Stereotactic radiosurgery group
Patients with unilateral Vestibular Schwannoma treated with stereotactic radiosurgery, as proposed by the institution's skull base tumor board independently of the study.
Wait and scan group
Patients with unilateral Vestibular Schwannoma followed with an MRI-based observation strategy, as proposed by the institution's skull base tumor board independently of the study.
Sponsors
Leads: University Hospital, Geneva

This content was sourced from clinicaltrials.gov