Learn About Sea-Blue Histiocytosis

What is the definition of Sea-Blue Histiocytosis?
Sea-Blue histiocytosis, also known as inherited lipemic splenomegaly, is an extremely rare condition characterized by elevated triglyceride levels (hypertriglyceridemia) and an enlarged spleen (splenomegaly). The disorder is so named because certain white blood cells, known as histiocytes, appear bright blue when stained and viewed under the microscope. Additional signs and symptoms may include a low platelet count (thrombocytopenia), liver function abnormalities, and heart disease. It is one of a group of related fat (lipid) disorders caused by certain changes in the APOE gene. The genetic change associated with this condition is inherited in an autosomal dominant manner though other factors, such as a patient's gender, the patient's lipid levels, and the genetic makeup of the other APOE gene may play a role in how the condition is expressed.
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What are the alternative names for Sea-Blue Histiocytosis?
  • Sea-Blue histiocytosis
  • Histiocytosis, sea-blue
  • Inherited Lipemic Splenomegaly
  • Sea-Blue histiocyte disease
Who are the top Sea-Blue Histiocytosis Local Doctors?
IW
Dr. Ilene C. Weitz
Hematology
Distinguished
Highly rated in
37
conditions
Hematology

Keck Medicine of USC

USC Norris Comprehensive Cancer Center & Hospital

1441 Eastlake Ave, 
Los Angeles, CA 

Ilene Weitz is a Hematologist in Los Angeles, California. Weitz has been practicing medicine for over 47 years and is rated as a Distinguished expert by MediFind in the treatment of Sea-Blue Histiocytosis. She is also highly rated in 37 other conditions, according to our data. Her top areas of expertise are Paroxysmal Nocturnal Hemoglobinuria (PNH), Hemolytic Anemia, Atypical Hemolytic Uremic Syndrome (aHUS), Bone Marrow Aspiration, and Bone Marrow Transplant. She is licensed to treat patients in California. Weitz is currently accepting new patients.

JL
Jane L. Liesveld
Dr. Jane L. Liesveld
Hematology | Oncology
Distinguished
Highly rated in
39
conditions
Hematology
Oncology

University of Rochester Medical Center

Strong Memorial Hospital

601 Elmwood Ave, 
Rochester, NY 

Jane Liesveld is a Hematologist and an Oncologist in Rochester, New York. Liesveld has been practicing medicine for over 43 years and is rated as a Distinguished expert by MediFind in the treatment of Sea-Blue Histiocytosis. She is also highly rated in 39 other conditions, according to our data. Her top areas of expertise are Acute Myeloid Leukemia (AML), Acute Myeloblastic Leukemia without Maturation, Acute Myeloblastic Leukemia with Maturation, Bone Marrow Transplant, and Bone Marrow Aspiration. She is licensed to treat patients in New York. Liesveld is currently accepting new patients.

 
 
 
 
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EJ
Dr. Eric D. Jacobsen
Hematology Oncology | Hematology | Oncology
Distinguished
Highly rated in
29
conditions
Hematology Oncology
Hematology
Oncology

Davenport-Mugar Cancer Center Cape Cod Hospital

27 Park St, 
Hyannis, MA 

Eric Jacobsen is a Hematologist Oncology specialist and a Hematologist in Hyannis, Massachusetts. Jacobsen has been practicing medicine for over 24 years and is rated as a Distinguished expert by MediFind in the treatment of Sea-Blue Histiocytosis. He is also highly rated in 29 other conditions, according to our data. His top areas of expertise are Follicular Lymphoma, Langerhans Cell Histiocytosis, Large-Cell Immunoblastic Lymphoma, Bone Marrow Transplant, and Bone Marrow Aspiration. He is licensed to treat patients in Massachusetts. Jacobsen is currently accepting new patients.

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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center

What are the Latest Advances for Sea-Blue Histiocytosis?

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