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Learn About Sea-Blue Histiocytosis

What is the definition of Sea-Blue Histiocytosis?
Sea-Blue histiocytosis, also known as inherited lipemic splenomegaly, is an extremely rare condition characterized by elevated triglyceride levels (hypertriglyceridemia) and an enlarged spleen (splenomegaly). The disorder is so named because certain white blood cells, known as histiocytes, appear bright blue when stained and viewed under the microscope. Additional signs and symptoms may include a low platelet count (thrombocytopenia), liver function abnormalities, and heart disease. It is one of a group of related fat (lipid) disorders caused by certain changes in the APOE gene. The genetic change associated with this condition is inherited in an autosomal dominant manner though other factors, such as a patient's gender, the patient's lipid levels, and the genetic makeup of the other APOE gene may play a role in how the condition is expressed.
What are the alternative names for Sea-Blue Histiocytosis?
  • Sea-Blue histiocytosis
  • Histiocytosis, sea-blue
  • Inherited Lipemic Splenomegaly
  • Sea-Blue histiocyte disease
Who are the top Sea-Blue Histiocytosis Local Doctors?
Advanced in Sea-Blue Histiocytosis
Dermatology
Advanced in Sea-Blue Histiocytosis
Dermatology
225 E Chicago Ave, 
Chicago, IL 
Languages Spoken:
English, Polish, Spanish

Lacey Kruse is a Dermatologist in Chicago, Illinois. Dr. Kruse is rated as an Advanced provider by MediFind in the treatment of Sea-Blue Histiocytosis. Her top areas of expertise are Familial Multiple Nevi Flammei, Stork Bite, Linear Hamartoma Syndrome, and Vascular Birthmark.

Advanced in Sea-Blue Histiocytosis
Hematology Oncology | Hematology | Oncology
Advanced in Sea-Blue Histiocytosis
Hematology Oncology | Hematology | Oncology
2 Independence Dr, 
Kennebunk, ME 
Languages Spoken:
English

Julio Hajdenberg is a Hematologist Oncology specialist and a Hematologist in Kennebunk, Maine. Dr. Hajdenberg is rated as an Advanced provider by MediFind in the treatment of Sea-Blue Histiocytosis. His top areas of expertise are Histiocytosis, Reticulohistiocytoma, Factor 5 Deficiency, Prostate Cancer, and Bone Marrow Aspiration.

 
 
 
 
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Stephen J. Forman
Experienced in Sea-Blue Histiocytosis
Experienced in Sea-Blue Histiocytosis

City Of Hope Medical Foundation

1500 Duarte Rd, 
Duarte, CA 
Languages Spoken:
English
Offers Telehealth

Stephen Forman is a Hematologist in Duarte, California. Dr. Forman is rated as an Experienced provider by MediFind in the treatment of Sea-Blue Histiocytosis. His top areas of expertise are Non-Hodgkin Lymphoma, Acute Myeloid Leukemia (AML), Graft Versus Host Disease (GvHD), Bone Marrow Transplant, and Bone Marrow Aspiration.

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Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center