Hybrid Micro-macro Electrodes to Record the Activity of Single Neurons During Seizures in Patients Who Suffer from Epilepsy

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The aim of the MicroEPI study is to know whether it is possible to use safely a medical device (a micro-electrode) that allows recording the activity of neurons in the human brain. Patients who suffer from drug-resistant epilepsy and who are candidates to epilepsy surgery to alleviate their condition sometimes require the implantation of intracranial EEG electrodes for a few weeks, in order to determine as best as possible which region of the brain to operate on. In the MicroEPI study, some of these electrodes will also comprise micro-electrodes, allowing us to record the activity of the patients' neurons during their epileptic seizures.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Patient 18 years old or older suffering from drug-resistant focal epilepsy.

• Candidate for epilepsy surgery.

• Requires evaluation with intracranial stereo-EEG electrodes.

• Able and willing to provide informed consent.

Locations
Other Locations
Switzerland
Inselspital Bern
RECRUITING
Bern
Hôpitaux Universitaires de Genève
RECRUITING
Geneva
Contact Information
Primary
Pierre Mégevand, MD, PhD
pierre.megevand@unige.ch
+41 22 379 53 88
Time Frame
Start Date: 2023-03-30
Estimated Completion Date: 2027-09
Participants
Target number of participants: 30
Treatments
Experimental: micro-macro electrode
In this single-arm, open-label study, all patients receive one or a handful of micro-macro electrode (MME) in place of conventional intracranial EEG electrodes.
Related Therapeutic Areas
Sponsors
Leads: Pierre Mégevand
Collaborators: Swiss National Science Foundation, Wyss Center for Bio and Neuroengineering

This content was sourced from clinicaltrials.gov