Pilot Study of Transcranial Direct Current Stimulation (tDCS) to Treat Epilepsy
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The purpose of this research is to see to what extent electrical stimulation applied to the scalp (transcranial direct current stimulation or tDCS) can reduce the number and intensity of epileptic seizures.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 6
Healthy Volunteers: f
View:
• Clinical diagnosis of generalized onset or focal epilepsy or sleep-related epileptic encephalopathy.
• Estimated to have at least 2 countable seizures per month or spike-wave index ≥50%.
• Has not had control with at least 2 anti-seizure medicines.
• Able to maintain a constant medication for duration of the study (rescue meds allowed).
• Subject or legally authorized representative is able to understand consent and keep a seizure diary in English.
Locations
United States
Minnesota
Mayo Clinic Minnesota
RECRUITING
Rochester
Contact Information
Primary
Precylla Ruiz
ruiz.precylla@mayo.edu
507-538-6606
Backup
Izzie Meunier
meunier.isabelle@mayo.edu
507-538-6337
Time Frame
Start Date: 2023-04-12
Estimated Completion Date: 2026-02
Participants
Target number of participants: 30
Treatments
Experimental: tDCS Treatment A (Low Amplitude)
Subjects with focal epilepsy that is not well-controlled on anti-seizure medications will receive 2 different treatments periods, each lasting 2 months, of transcranial direct current stimulation (tDCS). The initial treatment stimulation will be completed during the first 2-months.
Experimental: tDCS Treatment B (High Amplitude)
Subjects with focal epilepsy that is not well-controlled on anti-seizure medications will receive 2 different treatments periods, each lasting 2 months, of transcranial direct current stimulation (tDCS). The last treatment stimulation will be completed during the following 2-months.
Sponsors
Leads: Mayo Clinic