An Open Label Benzodiazepine Study for the Treatment of Seizure Clusters in a Third Level Mexican Neurological Center
Status: Recruiting
Location: See location...
Intervention Type: Drug, Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The aim of this study is to determine the efficacy in seizure reduction when comparing orodispersable clonazepam versus usual treatment (i.e. medication load, intravenous high- dose benzodiazepines) of seizure clusters in a third level center of care in Mexico city.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• At least age of 18
• Patient available for follow-up
• Previous diagnosis of epilepsy
• Patient meets criteria for seizure clusters (3 or more seizures in a period of 24 hours)
Locations
Other Locations
Mexico
Instituto Nacional de Neurología y Neurocirugía Dr. Manuel Velasco Suárez
RECRUITING
Mexico City
Contact Information
Primary
Elma M Paredes-Aragón, MD
elma.paredes@innn.edu.mx
5556063822
Backup
Juan C Lopez Hernandez, MD
juanca9684@hotmail.com
5556063822
Time Frame
Start Date: 2023-05-01
Estimated Completion Date: 2024-12-31
Participants
Target number of participants: 150
Treatments
Experimental: Orodispersable clonazepam
50 patients will receive oral orodispersable clonazepam.
Experimental: Buccal midazolam
50 patients will receive buccal midazolam.
Active_comparator: Conventional treatment
50 patients will receive usual/ conventional treatment of seizure clusters
Related Therapeutic Areas
Sponsors
Leads: El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez