Non-Helium Magnetoencephalography for Clinical Management of Refractory Epilepsy in Children: An Observational Cohort Study

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY

The goal of this observational study is to evaluate the effectiveness of Magnetoencephalography (MEG) in the preoperative assessment of children with refractory epilepsy, particularly in identifying the seizure focus, and to compare it with the gold standard methods of Stereo-electroencephalography (SEEG) and Electrocorticography (ECoG). The main questions this study aims to answer are: 1. How consistent is MEG with SEEG/ECoG in locating the epileptic focus in children with refractory epilepsy? 2. What is the clinical efficacy of MEG in identifying epileptic foci? Participants will: 1. Be divided into 2 groups: the case group and the control group. Participants in the case group will undergo both MEG and SEEG/ECoG for preoperative assessment, while patients in the control group will undergo only SEEG/ECoG before surgery. 2. Be followed up at 1, 3, 6, and 12 months after surgery to assess seizure control, neurological function, and quality of life.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 3
Maximum Age: 18
Healthy Volunteers: f
View:

• Age range: 3-18 years old;

• Clinically diagnosed with refractory epilepsy;

• Capable of cooperating with magnetoencephalography evaluation and recording.

Locations
Other Locations
China
Guangzhou Women and Children's medical center
RECRUITING
Guangzhou
Contact Information
Primary
Ye Song, Medical Doctor
15625984282@163.com
+86-020-81886332
Time Frame
Start Date: 2024-11-05
Estimated Completion Date: 2027-12-31
Participants
Target number of participants: 100
Treatments
Case
Participants in the case group will undergo both MEG and SEEG/ECoG for preoperative assessment.
Control
Patients in the control group will undergo only SEEG/ECoG before surgery.
Related Therapeutic Areas
Sponsors
Leads: Guangzhou Women and Children's Medical Center
Collaborators: Beijing X-Magtech Technology Limited

This content was sourced from clinicaltrials.gov