Nordic Study of the Cerebellar Mutism Syndrome in Children With Brain Tumours of the Posterior Fossa
Status: Recruiting
Location: See all (29) locations...
Study Type: Observational
SUMMARY
The purpose of this study is to determine why up to 25% of the pediatric patients who have surgery for a tumor in the posterior fossa develops the Cerebellar Mutism Syndrome (CMS). Furthermore the purpose is to explore the clinical course and the best treatment of the syndrome.
Eligibility
Participation Requirements
Sex: All
Maximum Age: 18
Healthy Volunteers: f
View:
• Age \< 18 years at the date of first imaging showing this tumour
• Tumour in the cerebellum/4th ventricle/brainstem with intention to treat with surgical resection or open biopsy. Second and further surgeries are also included.
• Informed consent from custodial parent(s)
Locations
Other Locations
Austria
Medical University of Vienna
RECRUITING
Vienna
Belgium
University Hospital Leuven
RECRUITING
Leuven
Denmark
Aalborg University Hospital
RECRUITING
Aalborg
Aarhus University Hospital
RECRUITING
Aarhus
Rigshospitalet
RECRUITING
Copenhagen
Odense University Hospital
RECRUITING
Odense
Finland
Helsinki University Central Hospital
RECRUITING
Helsinki
Kuopio University Hospital
NOT_YET_RECRUITING
Kuopio
Oulu University Hospital
NOT_YET_RECRUITING
Oulu
Tampere University Hospital
NOT_YET_RECRUITING
Tampere
Turku University Hospital
NOT_YET_RECRUITING
Turku
Germany
University of Leipzig Medical Center
RECRUITING
Leipzig
Hungary
Semmelweis University, 2nd Dept of Pediatrics
RECRUITING
Budapest
Italy
Ospedale Pediatrico Bambino Gesù
RECRUITING
Rome
Lithuania
Hospital of Lithuanian University of Health Sciences Kauno klinikos
RECRUITING
Kaunas
Netherlands
UMC Groningen
ACTIVE_NOT_RECRUITING
Groningen
Radboud University Nijmegen Medical Centre
RECRUITING
Nijmegen
UMC Utrecht
RECRUITING
Utrecht
Norway
Haukeland University Hospital
RECRUITING
Bergen
Oslo University Hospital
NOT_YET_RECRUITING
Oslo
University Hospital of North Norway
NOT_YET_RECRUITING
Tromsø
St. Olav's Hospital
RECRUITING
Trondheim
Sweden
Sahlgrenska University Hospital
RECRUITING
Gothenburg
Linköping University Hospital
RECRUITING
Linköping
Skåne University Hospital
RECRUITING
Skåne
Karolinska University Hospital
RECRUITING
Stockholm
University Hospital of Umeå
RECRUITING
Umeå
Uppsala University Hospital
RECRUITING
Uppsala
United Kingdom
Alder Hey Childrens NHS Foundation Trust
RECRUITING
Liverpool
Contact Information
Primary
Aske F Laustsen, MD, PhD stud
aske.foldbjerg.laustsen@regionh.dk
+45 40218998
Backup
Astrid M Sehested, MD
astrid.marie.sehested@regionh.dk
+45 35451367
Time Frame
Start Date: 2014-10
Estimated Completion Date: 2028-12-31
Participants
Target number of participants: 1000
Treatments
Posterior fossa tumor patients
Children (0-18 years) with a tumour in the posterior fossa (cerebellum/4th ventricle/brainstem ) requiring surgery or open biopsy at one of the participating centres.
Authors
Related Therapeutic Areas
Sponsors
Collaborators: University Hospital Birmingham, Oulu University Hospital, Tampere University Hospital, Uppsala University Hospital, University Hospitals Bristol and Weston NHS Foundation Trust, Skane University Hospital, Aarhus University Hospital, University Hospital of North Norway, University Hospital Tuebingen, Ospedale Pediatrico Bambin Gesù, Medical University of Vienna, Vienna University Hospital, Austria, Universitaire Ziekenhuizen KU Leuven, Turku University Hospital, Queen Fabiola Children's University Hospital, Aalborg University Hospital, Sahlgrenska University Hospital, Royal Infirmary of Edinburgh, CHC MontLégia, Motol University Hospital, South Glasgow University Hospitals NHS Trust, University Hospital, Umeå, Karolinska University Hospital, Odense University Hospital, Radboud University Medical Center, University of Leipzig Medical Center, Helsinki University Central Hospital, University Hospital, Ghent, Nottingham University Hospitals NHS Trust, Great Ormond Street Hospital for Children NHS Foundation Trust, Cliniques universitaires Saint-Luc- Université Catholique de Louvain, Haukeland University Hospital, Trondheim University Hospital, Liverpool University Hospitals NHS Foundation Trust, University Hospital, Linkoeping, Hospital Sant Joan de Deu, Oslo University Hospital, University Hospital, Antwerp, Technical University of Denmark, Hospital De La Citadelle, Kuopio University Hospital
Leads: Rigshospitalet, Denmark