Use of Renin Versus Lactic Acid as Tissue Perfusion Biomarkers for Mortality Prediction in Hypotensive Critically Ill Patients
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY
Measurement of Whole Blood Lactate Concentrations Whole blood lactate concentrations will be measured at the time of study enrollment and at 24, 48, and 72 hours. Measurement of Plasma Renin Concentrations Serum renin concentration will be measured on blood samples drawn from arterial catheters on supine position right after inclusion. Discarded whole blood samples (waste blood samples) in EDTA tubes are prospectively collected from each patient at the time of study enrollment and at 24, 48, and 72 hours.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 21
Maximum Age: 60
Healthy Volunteers: f
View:
• Patients aged 21-60 years old
• Those receiving vasopressors for greater than or equal to 6 hours to maintain a mean arterial pressure (MAP) ≥65 mm Hg.
• Anticipated stay \>24 hours.
Locations
Other Locations
Egypt
Azhar unversity
COMPLETED
Cairo
Azhar University
RECRUITING
Madīnat An Naşr
Contact Information
Primary
Abd El-Wahab AS Mohammed, AP
abdelwahabsaleh7020@gmail.com
+2(045)33343945
Time Frame
Start Date: 2022-06-21
Estimated Completion Date: 2024-01-25
Participants
Target number of participants: 84
Treatments
Renin group and lactate group
Renin group and lactate group
Related Therapeutic Areas
Sponsors
Leads: Al-Azhar University